http://www.cnr.it/ontology/cnr/individuo/prodotto/ID23743
Predictive value of EuroScore on long term outcome in cardiac surgery patients: a single institution study (Articolo in rivista)
- Type
- Label
- Predictive value of EuroScore on long term outcome in cardiac surgery patients: a single institution study (Articolo in rivista) (literal)
- Anno
- 2005-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1136/hrt.2004.037135 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- De Maria R.; Mazzoni M.; Parolini M.; Gregori D.; Bertone F.; Arena V.; Parodi O. (literal)
- Pagina inizio
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- In: \"Heart \"91,2005,779-784 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- CNR Clinical Physiology Institute, Section of Milan, Niguarda Ca` Granda Hospital, Milan, Italy
Department of Anaesthesia and Intensive Care, Humanitas Gavazzeni, Bergamo, Italy
Department of Public Health and Microbiology, University of Turin, Turin, Italy
Department of Cardiac Surgery, Humanitas Gavazzeni, Bergamo, Italy (literal)
- Titolo
- Predictive value of EuroScore on long term outcome in cardiac surgery patients: a single institution study (literal)
- Abstract
- Objectives: To assess the value of the European system for cardiac operative risk evaluation (EuroSCORE),
a validated model for prediction of in-hospital mortality after cardiac surgery, in predicting long term
event-free survival.
Design and setting: Single institution observational cohort study.
Patients: Adult patients (n = 1230) who underwent cardiac surgery between January 2000 and August
2002.
Results: Mean age was 65 (11) years and 32% were women. Type of surgery was isolated coronary artery
bypass grafting in 62%, valve surgery in 23%, surgery on the thoracic aorta in 4%, and combined or other
procedures in 11%. Mean EuroSCORE was 4.53 (3.16) (range 0-21); 366 were in the low (0-2), 442 in
the medium (3-5), 288 in the high (6-8), and 134 in the very high risk group (> 9). Information on deaths
or events leading to hospital admission after the index discharge was obtained from the Regional Health
Database. Out of hospital deaths were identified through the National Death Index. In-hospital 30 day
mortality was 2.8% (n = 34). During 2024 person-years of follow up, 44 of 1196 patients discharged
alive (3.7%) died. By Cox multivariate analysis, EuroSCORE was the single best independent predictor of
long term all cause mortality (hazard ratio (HR) 1.55, 95% confidence interval (CI) 1.03 to 2.34,
p , 0.0001). In the time to first event analysis, 227 either died without previous events (n = 20, 9%) or
were admitted to hospital for an event (n = 207, 91%). EuroSCORE (HR 1.60, 95% CI 1.36 to 1.89,
p , 0.0001), the presence of > 2 co-morbidities versus one (HR 1.49, 95% CI 1.09 to 2.02,
p , 0.0001), and . 96 hours' stay in the intensive care unit after surgery (HR 2.04, 95% CI 1.42 to 2.95,
p = 0.0001) were independently associated with the combined end point of death or hospital admission
after the index discharge.
Conclusions: EuroSCORE and a prolonged intensive care stay after surgery are associated with long term
event-free survival and can be used to tailor long term postoperative follow up and plan resource
allocation for the cardiac surgical patient. (literal)
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