Multiple sclerosis patients express increased levels of beta-nerve growth factor in cerebrospinal fluid. (Articolo in rivista)

Type
Label
  • Multiple sclerosis patients express increased levels of beta-nerve growth factor in cerebrospinal fluid. (Articolo in rivista) (literal)
Anno
  • 1992-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/0304-3940(92)90762-V (literal)
Alternative label
  • Bracci Laudiero L (1), Aloe L (1), Levi-Montalcini R (1), Buttinelli C (2), Schilter D (3), Gillessen S (3), Otten U (3). (1992)
    Multiple sclerosis patients express increased levels of beta-nerve growth factor in cerebrospinal fluid.
    in Neuroscience letters (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Bracci Laudiero L (1), Aloe L (1), Levi-Montalcini R (1), Buttinelli C (2), Schilter D (3), Gillessen S (3), Otten U (3). (literal)
Pagina inizio
  • 9 (literal)
Pagina fine
  • 12 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 147 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 4 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 1 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • (1) Institute of Neurobiology, CNR, Rome, Italy. (2) Department of Newurological Sciences. Universita' La Sapienza Rome, Italy (3) Department of Physiology, University of Basel, Basel, Switzerland (literal)
Titolo
  • Multiple sclerosis patients express increased levels of beta-nerve growth factor in cerebrospinal fluid. (literal)
Abstract
  • We describe the measurement of beta-nerve growth factor (NGF) content in cerebrospinal fluid (CSF) from multiple sclerosis (MS) patients compared with CSF from age-matched normal subjects using a specific sandwich immunoassay (ELISA). During acute attacks patients exhibit a significant increase of NGF content compared to controls. In contrast during remission the mean NGF levels in CSF markedly decrease. These results strongly indicate that increased NGF production in CSF is a characteristic feature of the MS inflammatory response. (literal)
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