http://www.cnr.it/ontology/cnr/individuo/prodotto/ID23705
Long-term survival of patients with chest pain syndrome and angiographically normal or near normal coronary arteries : the additional prognostic value of dipyridamole echocardiogrphy test (DET) (Articolo in rivista)
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- Long-term survival of patients with chest pain syndrome and angiographically normal or near normal coronary arteries : the additional prognostic value of dipyridamole echocardiogrphy test (DET) (Articolo in rivista) (literal)
- Anno
- 2005-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1093/eurheartj/ehi408 (literal)
- Alternative label
Sicari R.; Palikas A.; Pasanisi E.; Venneri L.; Picano E. (2005)
Long-term survival of patients with chest pain syndrome and angiographically normal or near normal coronary arteries : the additional prognostic value of dipyridamole echocardiogrphy test (DET)
in European heart journal; Oxford University Press, Oxford (Regno Unito)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Sicari R.; Palikas A.; Pasanisi E.; Venneri L.; Picano E. (literal)
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- http://eurheartj.oxfordjournals.org/content/26/20/2136.long (literal)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- In: \"Eur Heart J\",26 2005,20,2136-2141 (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- CNR, Institute of Clinical Physiology, Pisa, Italy; and Internal Medicine Department, Elisabeth Hospital, Hodmezovasarhely, Hungary (literal)
- Titolo
- Long-term survival of patients with chest pain syndrome and angiographically normal or near normal coronary arteries : the additional prognostic value of dipyridamole echocardiogrphy test (DET) (literal)
- Abstract
- Aims Patients with normal coronary arteries have a heterogeneous prognosis. Aim of this study was to
assess whether dipyridamole stress echocardiography positivity identifies a prognostically less benign
subset.
Methods and results We selected 457 patients (245 males; 56+10 years) who underwent stress highdose
dipyridamole echocardiography and had angiographically non-significant (,50% visually assessed)
stenosis in any major vessel and preserved left ventricular function. All patients were followed up for a
median of 7.1 years (first quartile 5 and third quartile 10.5). Dipyridamole echocardiography test (DET)
positivity for regional dysfunction occurred in 43(9%) patients. Kaplan-Meier survival estimates showed
a significant better outcome for those patients with negative dipyridamole echocardiography test compared
with those with a positive test (90 vs. 75.7%, at 140 months of follow-up, P ¼ 0.0018). At multivariable
analysis, mild or moderate irregularity on coronary arteriogram (HR ¼ 3.3, CI 95% ¼ 1.7-6.2),
diabetes (HR ¼ 3.5, CI 95% ¼ 1.4-9.2), and wall motion score index at peak stress (HR ¼ 6.7, CI
95% ¼ 2.5-17.8) were independent predictors of all-cause death.
Conclusion DET adds incremental value to the prognostic stratification achieved with clinical and angiographic
data in the subset of patients with normal or near-normal coronary arteries. (literal)
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