Long-term survival of patients with chest pain syndrome and angiographically normal or near normal coronary arteries : the additional prognostic value of dipyridamole echocardiogrphy test (DET) (Articolo in rivista)

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  • Long-term survival of patients with chest pain syndrome and angiographically normal or near normal coronary arteries : the additional prognostic value of dipyridamole echocardiogrphy test (DET) (Articolo in rivista) (literal)
Anno
  • 2005-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1093/eurheartj/ehi408 (literal)
Alternative label
  • Sicari R.; Palikas A.; Pasanisi E.; Venneri L.; Picano E. (2005)
    Long-term survival of patients with chest pain syndrome and angiographically normal or near normal coronary arteries : the additional prognostic value of dipyridamole echocardiogrphy test (DET)
    in European heart journal; Oxford University Press, Oxford (Regno Unito)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Sicari R.; Palikas A.; Pasanisi E.; Venneri L.; Picano E. (literal)
Pagina inizio
  • 2136 (literal)
Pagina fine
  • 2141 (literal)
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  • http://eurheartj.oxfordjournals.org/content/26/20/2136.long (literal)
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  • 26 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: \"Eur Heart J\",26 2005,20,2136-2141 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR, Institute of Clinical Physiology, Pisa, Italy; and Internal Medicine Department, Elisabeth Hospital, Hodmezovasarhely, Hungary (literal)
Titolo
  • Long-term survival of patients with chest pain syndrome and angiographically normal or near normal coronary arteries : the additional prognostic value of dipyridamole echocardiogrphy test (DET) (literal)
Abstract
  • Aims Patients with normal coronary arteries have a heterogeneous prognosis. Aim of this study was to assess whether dipyridamole stress echocardiography positivity identifies a prognostically less benign subset. Methods and results We selected 457 patients (245 males; 56+10 years) who underwent stress highdose dipyridamole echocardiography and had angiographically non-significant (,50% visually assessed) stenosis in any major vessel and preserved left ventricular function. All patients were followed up for a median of 7.1 years (first quartile 5 and third quartile 10.5). Dipyridamole echocardiography test (DET) positivity for regional dysfunction occurred in 43(9%) patients. Kaplan-Meier survival estimates showed a significant better outcome for those patients with negative dipyridamole echocardiography test compared with those with a positive test (90 vs. 75.7%, at 140 months of follow-up, P ¼ 0.0018). At multivariable analysis, mild or moderate irregularity on coronary arteriogram (HR ¼ 3.3, CI 95% ¼ 1.7-6.2), diabetes (HR ¼ 3.5, CI 95% ¼ 1.4-9.2), and wall motion score index at peak stress (HR ¼ 6.7, CI 95% ¼ 2.5-17.8) were independent predictors of all-cause death. Conclusion DET adds incremental value to the prognostic stratification achieved with clinical and angiographic data in the subset of patients with normal or near-normal coronary arteries. (literal)
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