Monosodium glutamate increases NGF and NPY concentrations in rat hypothalamus and pituitary. (Articolo in rivista)

Type
Label
  • Monosodium glutamate increases NGF and NPY concentrations in rat hypothalamus and pituitary. (Articolo in rivista) (literal)
Anno
  • 1995-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1097/00001756-199512150-00003 (literal)
Alternative label
  • Tirassa P(1,2), Lundeberg T (3), Stenfors C (2), Bracci-Laudiero L (1,2), Theodorsson E (4), Aloe L (1) (1995)
    Monosodium glutamate increases NGF and NPY concentrations in rat hypothalamus and pituitary.
    in NeuroReport (Oxf.)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Tirassa P(1,2), Lundeberg T (3), Stenfors C (2), Bracci-Laudiero L (1,2), Theodorsson E (4), Aloe L (1) (literal)
Pagina inizio
  • 2450 (literal)
Pagina fine
  • 2452 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 6 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 3 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 18 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • (1)Institute of Neurobiology, CNR, Rome, Italy (2) Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden (3) Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (4) Department of Clinical Chemistry, University Hospital, Linkoping, Sweden (literal)
Titolo
  • Monosodium glutamate increases NGF and NPY concentrations in rat hypothalamus and pituitary. (literal)
Abstract
  • The effects of MSG treatment on NGF and NPY levels were analysed in the hypothalamus, pituitary, adrenal, thyroid and testis of adult rats. Daily i.v. injections of MSG (1 g kg-1 for 1 week) induced an increase of NGF in the hypothalamus (control (C) = 378 +/- 54; saline (S) = 369 +/- 36; MSG = 479 +/- 35 pg g-1 tissue; p < 0.001) and pituitary (C = 310 +/- 34; S = 376 +/- 114; MSG = 576 +/- 98 pg g-1 tissue; p < 0.01). Hypothalamic and pituitary NPY concentrations were also altered in the MSG-treated rats. Compared with saline-treated rats, the NPY concentration increased by 43% in the hypothalamus and 37.5% in the pituitary of MSG-treated rats. No significant changes in NGF and NPY content were found in the adrenal or thyroid of treated animals. These results suggest that hypothalamic and pituitary NGF and NPY levels may be involved in the control of neuroendocrine functions that are affected by MSG treatment. (literal)
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