http://www.cnr.it/ontology/cnr/individuo/prodotto/ID23636

An 8-yr follow-up of CO diffusing capacity in a general population sample of North Italy (Articolo in rivista)

Type

Articolo in rivista (Classe)
Prodotto della ricerca (Classe)

Label

An 8-yr follow-up of CO diffusing capacity in a general population sample of North Italy (Articolo in rivista) (literal)

Anno

2001-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1378/chest.120.1.74 (literal)

Alternative label

Viegi G*, Sherrill DL**, Carrozzi L***, Di Pede F***, Pedreschi M***, Baldacci S*, Pistelli F***, Enright P**. (2001)
An 8-yr follow-up of CO diffusing capacity in a general population sample of North Italy
in Chest (Amer. Coll. Chest Phys.)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Viegi G*, Sherrill DL**, Carrozzi L***, Di Pede F***, Pedreschi M***, Baldacci S*, Pistelli F***, Enright P**. (literal)

Pagina inizio

74 (literal)

Pagina fine

80 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

IMPACT FACTOR = 2.480 CITED HALF-LIFE = 7.2 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

120 (literal)

Rivista

Chest (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

7 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

1 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto

questo lavoro descrive specificatamente landamento longitudinale della capacità di diffusione alveolo-capillare, un test di funzione respiratoria globale abbastanza utilizzato in clinica, ma poco in epidemiologia. Infatti, esistono dati epidemiologici per sole 3 popolazioni: la nostra, italiana; quella norvegese; quella americana. Loriginalità del lavoro è data dal fatto che lanalisi longitudinale dei dati epidemiologici, prima di questo articolo, era stata eseguita solo sulla popolazione americana. Il carattere interdisciplinare internazionale è dato dalla collaborazione di epidemiologi e fisiopatologi respiratori italiani con un esperto biostatistico americano. (literal)

Note

ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

*CNR Institute of Clinical Physiology, Pisa, Italy; **Univ. of Arizona, Respiratory Sciences Center, Tucson, USA; *** Cardiothoracic Dept. Univ. and Hospital of Pisa, Italy. (literal)

Titolo

An 8-yr follow-up of CO diffusing capacity in a general population sample of North Italy (literal)

Abstract

STUDY OBJECTIVE: Diffusing capacity of the lung for carbon monoxide (DLCO) is frequently assessed as part of a thorough pulmonary function assessment in patients with pulmonary or cardiopulmonary diseases. However, little information regarding the longitudinal trends of DLCO is available. In this study, we examined the temporal trends in DLCO to determine the effects of smoking and changes in smoking habits. DESIGN: A longitudinal study was recently conducted in the Po River Delta area of northern Italy, in which DLCO measurements were taken approximately 8 years apart in the same subjects; this offered the unique opportunity to assess the temporal changes in DLCO. The longitudinal DLCO data were analyzed independently in two age groups (20 to 40 years, and > or = 40 years) using a repeated-measures analysis. RESULTS: Included were 928 subjects > 20 years old who had DLCO assessments both at baseline and follow-up. Male subjects had higher mean levels of DLCO than female subjects in the older age group (> or = 40 years). Continuous smokers had significantly lower DLCO levels than \"never-smokers,\" but their changes in DLCO during follow-up were the same. This suggests that the lung damage due to smoking had occurred prior to DLCO testing. We also found that the annual decline in DLCO accelerated with age in adults > or = 40 years old. CONCLUSIONS: We conclude that in adults > or = 40 years of age from the general population, DLCO accelerates downwards regardless of gender, smoking, and initial FEV(1) level. (literal)

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