Nerve growth factor stimulates production of neuropeptide Y in human lymphocytes. (Articolo in rivista)

Type
Label
  • Nerve growth factor stimulates production of neuropeptide Y in human lymphocytes. (Articolo in rivista) (literal)
Anno
  • 1996-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1097/0001756-199601310-00026 (literal)
Alternative label
  • Bracci-Laudiero L (1,2), Aloe L (1), Stenfors C (2), Tirassa P (1), Theodorsson E (3), Lundberg T (2). (1996)
    Nerve growth factor stimulates production of neuropeptide Y in human lymphocytes.
    in NeuroReport (Oxf.)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Bracci-Laudiero L (1,2), Aloe L (1), Stenfors C (2), Tirassa P (1), Theodorsson E (3), Lundberg T (2). (literal)
Pagina inizio
  • 485 (literal)
Pagina fine
  • 488 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 7 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 4 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 2 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • (1) Institute of Neurobiology CNR, Rome, Italy. (2) Karolinska Institutet, Stockholm, Sweden. (3) University Hospital, Linkoping, Sweden (literal)
Titolo
  • Nerve growth factor stimulates production of neuropeptide Y in human lymphocytes. (literal)
Abstract
  • The production of neuropeptide Y (NPY) in lymphocytes obtained from human tonsils was investigated using radioimmunoassay. While unstimulated lymphocytes did not produce detectable amounts of NPY, NPY synthesis was induced after cell activation. Our results show that the addition of nerve growth factor (NGF) to unstimulated lymphocytes has an effect similar to that of mitogens, both leading to production of NPY. The study of purified B and T cells confirmed that only activated cells are able to synthesize NPY. The stimulatory effect of NGF on NPY production is not a common characteristic of all lymphocytes: only unstimulated T cells respond to NGF by synthesizing NPY. No such effects is seen in purified B cells. (literal)
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