http://www.cnr.it/ontology/cnr/individuo/prodotto/ID23470
Toward the effective surveillance of hypospadias (Articolo in rivista)
- Type
- Label
- Toward the effective surveillance of hypospadias (Articolo in rivista) (literal)
- Anno
- 2004-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1289/ehp.6398 (literal)
- Alternative label
Helen Dolk,1 Martine Vrijheid,2 John E.S. Scott,3 Marie-Claude Addor,4 Bev Botting,5 Catherine de Vigan,6
Hermien de Walle,7 Ester Garne,8 Maria Loane,1 Anna Pierini,9 Sixto Garcia-Minaur,10 Nigel Physick,11
Romano Tenconi,12 Awi Wiesel,13 Elisa Calzolari,14 and David Stone15 (2004)
Toward the effective surveillance of hypospadias
in Environmental health perspectives
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Helen Dolk,1 Martine Vrijheid,2 John E.S. Scott,3 Marie-Claude Addor,4 Bev Botting,5 Catherine de Vigan,6
Hermien de Walle,7 Ester Garne,8 Maria Loane,1 Anna Pierini,9 Sixto Garcia-Minaur,10 Nigel Physick,11
Romano Tenconi,12 Awi Wiesel,13 Elisa Calzolari,14 and David Stone15 (literal)
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- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14998760 (literal)
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- 1University of Ulster, Ulster, Northern Ireland, United Kingdom;2London School of Hygiene and Tropical Medicine, London, United Kingdom; 3Northern and Yorkshire Regional Health Authority, Newcastle upon Tyne, United Kingdom; 4Registre Vaudois des Malformations, Lausanne, Switzerland; 5Office for National Statistics, London, United Kingdom; 6INSERM, Paris, France; 7University of Groningen, Groningen, The Netherlands; 8University of Southern Denmark, Odense, Denmark; 9Institute of Clinical Physiology-CNR, Pisa, Italy; 10RACAV, Basque Country, Bilbao, Basque Country, Spain; 11England and Wales National Congenital Anomaly System, London, United Kingdom; 12Genetica Medica, University of Padova, Padova, Italy; 13 University of Mainz, Mainz, Germany; 14Istituto di Genetica Medica, University of Ferrara, Emilia Romagna, Italy; 15 Yorkhill Hospital, Glasgow, Scotland, United Kingdom (literal)
- Titolo
- Toward the effective surveillance of hypospadias (literal)
- Abstract
- Concern about apparent increases in the prevalence of hypospadias--a congenital male reproductive-tract abnormality--in the 1960s to 1980s and the possible connection to increasing exposures to endocrine-disrupting chemicals have underlined the importance of effective surveillance of hypospadias prevalence in the population. We report here the prevalence of hypospadias from 1980 to 1999 in 20 regions of Europe with EUROCAT (European Surveillance of Congenital Anomalies) population-based congenital anomaly registers, 14 of which implemented a guideline to exclude glanular hypospadias. We also report data from the England and Wales National Congenital Anomaly System (NCAS) . Our results do not suggest a continuation of rising trends of hypospadias prevalence in Europe. However, a survey of the registers and a special validation study conducted for the years 1994-1996 in nine EUROCAT registers as well as NCAS identified a clear need for a change in the guidelines for registration of hypospadias. We recommend that all hypospadias be included in surveillance, but that information from surgeons be obtained to verify location of the meatus, and whether surgery was performed, in order to interpret trends. Investing resources in repeated special surveys may be more cost-effective than continuous population surveillance. We conclude that it is doubtful whether we have had the systems in place worldwide for the effective surveillance of hypospadias in relation to exposure to potential endocrine-disrupting chemicals. (literal)
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