Cloning, expression and sequence homologies of cDNA for human gamma enolase. (Articolo in rivista)

Type
Label
  • Cloning, expression and sequence homologies of cDNA for human gamma enolase. (Articolo in rivista) (literal)
Anno
  • 1989-01-01T00:00:00+01:00 (literal)
Alternative label
  • Oliva D, Barba G, Barbieri G, Giallongo A, Feo S (1989)
    Cloning, expression and sequence homologies of cDNA for human gamma enolase.
    in Gene (Amst.); Elsevier, Amsterdam (Paesi Bassi)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Oliva D, Barba G, Barbieri G, Giallongo A, Feo S (literal)
Pagina inizio
  • 355 (literal)
Pagina fine
  • 360 (literal)
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  • 79 (literal)
Rivista
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  • 5 (literal)
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  • 2 (literal)
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  • Istituto di Biologia dello Sviluppo (Consiglio Nazionale delle Ricerche), Palermo, Italy. (literal)
Titolo
  • Cloning, expression and sequence homologies of cDNA for human gamma enolase. (literal)
Abstract
  • The nucleotide sequence of the human gamma-enolase mRNA was determined from recombinant cDNA clones. The sequence spans 2273 bp and includes the complete coding region of 1299 bp, a 5'-noncoding region of 74 bp and a 897-bp-long 3'-noncoding region containing a variant polyadenylation signal (ATTAAA). The deduced amino acid (aa) sequence is 433 aa long and shows a 97% similarity with rat gamma-enolase. Both the 5'- and 3'-untranslated regions are similar (82% and 68%, respectively) to the analogous regions of the rat gamma-enolase gene, suggesting that a strong selective pressure operates on noncoding segments of gamma-enolase mRNAs. The size of the gamma-enolase mRNA expressed in human brain is 2.4 kb. A crosshybridizing 1.5-kb message is detected in human skeletal muscle which may be derived from the beta-enolase-coding gene. (literal)
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