Antioxidant, antimicrobial and anti-proliferative activities of Solanum tuberosum L. var. Vitelotte (Articolo in rivista)

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Label
  • Antioxidant, antimicrobial and anti-proliferative activities of Solanum tuberosum L. var. Vitelotte (Articolo in rivista) (literal)
Anno
  • 2013-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.fct.2012.12.048 (literal)
Alternative label
  • Bontempo P, Carafa V, Grassi R, Basile A, Tenore GC, Formisano C, Rigano D, Altucci L. (2013)
    Antioxidant, antimicrobial and anti-proliferative activities of Solanum tuberosum L. var. Vitelotte
    in Food and chemical toxicology
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Bontempo P, Carafa V, Grassi R, Basile A, Tenore GC, Formisano C, Rigano D, Altucci L. (literal)
Pagina fine
  • 304 (literal)
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  • 55 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 312 (literal)
Note
  • PubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Department of General Pathology, Second University of Naples, Vico L. de Crecchio 7, 80138 Napoli, Italy Medical-Surgical Department of Internal and Experimental Clinic 'Magrassi-Lanzara', Second University of Naples, Via Pansini 5, 80100 Naples, Italy Department of Plant Biology, University of Naples \"Federico II\", Via Foria 223, 80139 Naples, Italy Department of Pharmaceutical Chemistry, University of Naples \"Federico II\", Via D. Montesano, 49, 80131 Naples, Italy Department of Chemistry of Natural Compounds, University of Naples \"Federico II\", Via D. Montesano, 49, 80131 Naples, Italy Institute of Genetics and Biophysics 'Adriano Buzzati Traverso', IGB, Via P. Castellino 111, 80131 Naples, Italy (literal)
Titolo
  • Antioxidant, antimicrobial and anti-proliferative activities of Solanum tuberosum L. var. Vitelotte (literal)
Abstract
  • Solanum tuberosum L. var. Vitelotte is a potato variety widely used for human consumption. The pigments responsible for its attractive color belong to the class of anthocyanins. The objectives of this study were to characterize and measure the concentration of anthocyanins in pigmented potatoes and to evaluate their antioxidant and antimicrobial activities and their anti-proliferative effects in solid and hematological cancer cell lines. Anthocyanins exert anti-bacterial activity against different bacterial strains and a slight activity against three fungal strains. The Gram-positive bacterium Staphylococcus aureus and the fungus Rhyzoctonia solani were the most affected microorganisms. Antioxidant activities were evaluated by DPPH and FRAP methods; the extract showed a higher reducing capability than anti-radical activity. Moreover, we found that in different cancer cell models the anthocyanins cause inhibition of proliferation and apoptosis in a dose dependent manner. These biological activities are likely due to the high content of malvidin 3-O-p-coumaroyl-rutinoside-5-O-glucoside and petunidin 3-O-p-coumaroyl-rutinoside-5-O-glucoside. (literal)
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