Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. (Articolo in rivista) (literal)

Anno

• 1994-01-01T00:00:00+01:00 (literal)

Alternative label

• Stahl N 1, Boulton TG 1, Farruggella T 1, Ip NY 1, Davis S 1, Witthuhn BA 2, Quelle FW 2, Silvennoinen O 2, Barbieri G 3, Pellegrini S 3, Ihle JN 2 and Yancopoulos GD 1. (1994)
  Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.
  in Science (New York, N.Y.); AAAS, American association for the advancement of science, Washington, DC (Stati Uniti d'America)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Stahl N 1, Boulton TG 1, Farruggella T 1, Ip NY 1, Davis S 1, Witthuhn BA 2, Quelle FW 2, Silvennoinen O 2, Barbieri G 3, Pellegrini S 3, Ihle JN 2 and Yancopoulos GD 1. (literal)

Pagina inizio

• 92 (literal)

Pagina fine

• 95 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 263 (literal)

Rivista

• Science (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 3 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 5143 (literal)

Note

• Google Scholar (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1 Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591. 2 St. Jude Children's Research Hospital, Department of Biochemistry, 332 North Lauderdale, Memphis, TN 38105. 3 Unité INSERM 276, Institut Pasteur,75724, Paris, CEDEX 15, France. (literal)

Titolo

• Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. (literal)

Abstract

• A recently defined family of cytokines, consisting of ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), oncostatin M (OSM), and interleukin-6 (IL-6), utilize the Jak-Tyk family of cytoplasmic tyrosine kinases. The beta receptor components for this cytokine family, gp130 and LIF receptor beta, constitutively associate with Jak-Tyk kinases. Activation of these kinases occurs as a result of ligand-induced dimerization of the receptor beta components. Unlike other cytokine receptors studied to date, the receptors for the CNTF cytokine family utilize all known members of the Jak-Tyk family, but induce distinct patterns of Jak-Tyk phosphorylation in different cell lines. (literal)

Editore

• AAAS, American association for the advancement of science (Editore)

Prodotto di

• Segnali cellulari critici nella biologia della cellula neoplastica (SV.P17.008.002) (Modulo)
• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)

Autore CNR

• GIOVANNA BARBIERI (Persona)

Incoming links:

Prodotto

• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)
• Segnali cellulari critici nella biologia della cellula neoplastica (SV.P17.008.002) (Modulo)

Autore CNR di

• GIOVANNA BARBIERI (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Science (Rivista)

Editore di

• AAAS, American association for the advancement of science (Editore)