Blue LED treatment of superficial abrasions (Contributo in atti di convegno)

Type
Label
  • Blue LED treatment of superficial abrasions (Contributo in atti di convegno) (literal)
Anno
  • 2013-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1117/12.2003933 (literal)
Alternative label
  • Domenico Alfieri ; Stefano Bacci ; Riccardo Cicchi ; Gaetano De Siena ; Virginia Lotti, Francesco Pavone ; Roberto Pini ; Francesca Rossi ; Francesca Tatini (2013)
    Blue LED treatment of superficial abrasions
    in SPIE Biomedical Optics 2013, Photonic Therapeutics and Diagnostics IX, San Francisco, CA, USA, 2 February 2013 through 7 February 2013
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Domenico Alfieri ; Stefano Bacci ; Riccardo Cicchi ; Gaetano De Siena ; Virginia Lotti, Francesco Pavone ; Roberto Pini ; Francesca Rossi ; Francesca Tatini (literal)
Pagina inizio
  • 85650H (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
  • Proc. SPIE 8565 \"Photonic Therapeutics and Diagnostics IX\" (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#volumeInCollana
  • 8565 (literal)
Note
  • Scopu (literal)
  • Google Scholar (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Institute of Applied Physics \"Nello Carrara\", Italian National Research Council, Via Madonna del Piano 10, I-50019 Sesto Fiorentino (FI) Italy Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, Laboratory of Histology, University of Florence, Viale Pieraccini 6, I-50139, Florence, Italy; Department of Preclinical and Clinical Pharmacology, University of Florence, Viale Pieraccini 6, I-50139, Florence, Italy European Laboratory for Non-linear Spectroscopy (LENS), Via Nello Carrara 1, I-50019, Sesto Fiorentino (Florence), Italy National Institute of Optics, National Research Council, Largo E. Fermi 6, I-50125, Florence, Italy Light4Tech Firenze S.r.L., Via Pisana 316, I-50018 Scandicci (FI) Italy. (literal)
Titolo
  • Blue LED treatment of superficial abrasions (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
  • 9780819493347 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#curatoriVolume
  • Andreas Mandelis; Anita Mahadevan-Jansen; Brian J. Wong; Henry Hirschberg M.D.; Hyun Wook Kang; Kenton W. Gregory M.D.; Melissa J. Suter; Nikiforos Kollias; Bernard Choi; Bodo E. Knudsen M.D.; E. Duco Jansen; Guillermo J. Tearney M.D.; Justus F. Ilgner M.D.; Steen J. Madsen; Stephen Lam; Haishan Zeng; Laura Marcu; Matthew Brenner (literal)
Abstract
  • A compact and easy-to-handle photocoagulation device was used for inducing an immediate coagulation effect in skin large superficial abrasions, reducing the recovering time and improving the wound healing process. The handheld illumination device consists of a high power LED, emitting in the blue region of the spectrum, mounted in a suitable and ergonomic case, together with power supply, electronics, and batteries. The working principle of the LED-based photocoagulator is a photothermal effect: the blue light is selectively absorbed by the haemoglobin content of the blood and then converted into heat. Here we present an in vivo study performed on animal models. 10 Sprague Dawley rats (Harlan, Italy, weighing 200-250 g) were used to study the wound healing process. On the back of each rat, four large abrasions were mechanically produced: two of them were used as a control, while the other two were treated with the photocoagulator, keeping it at a constant distance (2 mm) from the target, in continuous slow motion (treatment time: tens of seconds). The induced photothermal effect was monitored by an infrared thermocamera in order to avoid accidental thermal damage and to control the temperature dynamics during treatment. Objective observations, histopathological analysis and non-linear microscopy performed in a 8 days follow-up study showed no adverse reactions and no thermal damage in the treated areas and surrounding tissues. Moreover, a faster healing process and a better recovered morphology was evidenced in the treated tissue (literal)
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