Advanced composites for hard-tissue engineering based on PCL/organic-inorganic hybrid fillers: From the design of 2D substrates to 3D rapid prototyped scaffolds (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Advanced composites for hard-tissue engineering based on PCL/organic-inorganic hybrid fillers: From the design of 2D substrates to 3D rapid prototyped scaffolds (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1002/pc.22446 (literal)

Alternative label

• Roberto De Santis,1, A. Gloria 1, T. Russo 1, U. D'Amora 1, V. D'Antò 2, F. Bollino 3, M. Catauro 3, F. Mollica 4, S. Rengo 2, L. Ambrosio 1 (2013)
  Advanced composites for hard-tissue engineering based on PCL/organic-inorganic hybrid fillers: From the design of 2D substrates to 3D rapid prototyped scaffolds
  in Polymer composites
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Roberto De Santis,1, A. Gloria 1, T. Russo 1, U. D'Amora 1, V. D'Antò 2, F. Bollino 3, M. Catauro 3, F. Mollica 4, S. Rengo 2, L. Ambrosio 1 (literal)

Rivista

• Polymer composites (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1Institute of Composite and Biomedical Materials, National Research Council, 80125 Naples, Italy 2Department of Oral and Maxillofacial Sciences, University of Naples \"Federico II\", 80128 Naples, Italy 3Department of Mechanical and Aerospace Engineering, Second University of Naples, 81031 Aversa, Italy 4Department of Engineering, University of Ferrara, 44122, Ferrara, Italy (literal)

Titolo

• Advanced composites for hard-tissue engineering based on PCL/organic-inorganic hybrid fillers: From the design of 2D substrates to 3D rapid prototyped scaffolds (literal)

Abstract

• The bioactivity of sol-gel synthesized poly(?-caprolactone) (PCL)/TiO2 or poly(?-caprolactone)/ZrO2 particles was already known. In designing innovative 2D composite substrates for hard-tissue engineering, the possibility to embed PCL/TiO2 or PCL/ZrO2 hybrid fillers into a PCL matrix was previously proposed. In the present study, the potential of 3D fiber-deposition technique to design morphologically controlled scaffolds consisting of PCL reinforced with PCL/TiO2 or PCL/ZrO2 hybrid fillers was demonstrated. Finite element analysis was initially carried out on 2D substrates to find a correlation between the previously obtained results from the small punch test and the Young's modulus of the materials, whilst mechanical and biological tests were suitably performed on rapid prototyped scaffolds to assess the effects of the inclusion of the hybrid fillers on the performances of the 3D porous structures. The role of the inclusion of the hybrid fillers in improving the compressive modulus (about 90 MPa) and the cell viability/proliferation was demonstrated. (literal)

Prodotto di

• Institute for composite and biomedical materials (IMCB) (Istituto)
• Biomateriali ed ingegneria dei tessuti (PM.P02.004.002) (Modulo)

Autore CNR

• Ugo D'Amora (Unità di personale esterno)
• ANTONIO GLORIA (Unità di personale interno)
• TERESA RUSSO (Unità di personale esterno)
• LUIGI AMBROSIO (Unità di personale interno)
• ROBERTO DE SANTIS (Unità di personale interno)

Incoming links:

Prodotto

• Institute for composite and biomedical materials (IMCB) (Istituto)
• Biomateriali ed ingegneria dei tessuti (PM.P02.004.002) (Modulo)

Autore CNR di

• ROBERTO DE SANTIS (Unità di personale interno)
• LUIGI AMBROSIO (Unità di personale interno)
• TERESA RUSSO (Unità di personale esterno)
• Ugo D'Amora (Unità di personale esterno)
• ANTONIO GLORIA (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Polymer composites (Rivista)