A novel pseudoautosomal gene encoding a putative GTP-binding protein resides in the vicinity of the Xp/Yp telomere (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• A novel pseudoautosomal gene encoding a putative GTP-binding protein resides in the vicinity of the Xp/Yp telomere (Articolo in rivista) (literal)

Anno

• 1998-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1093/hmg/7.3.407 (literal)

Alternative label

• Gianfrancesco F, Esposito T, Montanini L, Ciccodicola A, Mumm S, Mazzarella R, Rao E, Giglio S, Rappold G, Forabosco A. (1998)
  A novel pseudoautosomal gene encoding a putative GTP-binding protein resides in the vicinity of the Xp/Yp telomere
  in Human molecular genetics (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Gianfrancesco F, Esposito T, Montanini L, Ciccodicola A, Mumm S, Mazzarella R, Rao E, Giglio S, Rappold G, Forabosco A. (literal)

Pagina inizio

• 407 (literal)

Pagina fine

• 414 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 7 (literal)

Rivista

• Human molecular genetics (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• [ 1 ] Univ Modena, Dept Morphol & Legal Med Sci, Histol Embryol & Genet Unit, I-41100 Modena, Italy Organization-Enhanced Name(s) University of Modena & Reggio Emilia [ 2 ] CNR, Int Inst Genet & Biophys, I-80125 Naples, Italy Organization-Enhanced Name(s) Consiglio Nazionale delle Ricerche (CNR) [ 3 ] Washington Univ, Sch Med, Div Bone & Mineral Dis, St Louis, MO 63110 USA Organization-Enhanced Name(s) Washington University [ 4 ] Washington Univ, Sch Med, Inst Biomed Comp, St Louis, MO 63110 USA Organization-Enhanced Name(s) Washington University [ 5 ] Washington Univ, Sch Med, Ctr Genet Med, St Louis, MO 63110 USA Organization-Enhanced Name(s) Washington University [ 6 ] Univ Heidelberg, Inst Human Genet, D-69120 Heidelberg, Germany Organization-Enhanced Name(s) Ruprecht Karl University Heidelberg [ 7 ] Univ Pavia, I-27100 Pavia, Italy (literal)

Titolo

• A novel pseudoautosomal gene encoding a putative GTP-binding protein resides in the vicinity of the Xp/Yp telomere (literal)

Abstract

• We report the cloning of a novel Xp/Yp pseudoautosomal gene called PGPL, and demonstrate that PGPL, like other pseudoautosomal genes, escapes X inactivation and has a functional homologue on the Y chromosome. This gene is expressed in all the tissues examined and is highly conserved across several species. The PGPL gene encodes a protein of 442 amino acids and shows the consensus sequences of a series of motifs of the GTP-binding protein domain. Using fluorescence in situ hybridization analysis on normal males and on patients with rearrangements in the pseudoautosomal region, the gene was localized within 500 kb of the telomere, Further refinement using a cosmid contig of the region places this novel gene within 80-110 kb of the telomere, making this the most telomeric gene on the short arms of the sex chromosomes. (literal)

Prodotto di

• Istituto di genetica e biofisica \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Autore CNR

• TERESA ESPOSITO (Unità di personale interno)
• ALFREDO CICCODICOLA (Persona)
• FERNANDO GIANFRANCESCO (Persona)

Incoming links:

Autore CNR di

• FERNANDO GIANFRANCESCO (Persona)
• ALFREDO CICCODICOLA (Persona)
• TERESA ESPOSITO (Unità di personale interno)

Prodotto

• Istituto di genetica e biofisica \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Human molecular genetics (Rivista)