A novel pseudoautosomal human gene encodes a putative protein similar to Ac-like transposases (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• A novel pseudoautosomal human gene encodes a putative protein similar to Ac-like transposases (Articolo in rivista) (literal)

Anno

• 1999-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1093/hmg/8.1.61 (literal)

Alternative label

• Esposito T, Gianfrancesco F, Ciccodicola A, Montanini L, Mumm S, D'Urso M, Forabosco A. (1999)
  A novel pseudoautosomal human gene encodes a putative protein similar to Ac-like transposases
  in Human molecular genetics (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Esposito T, Gianfrancesco F, Ciccodicola A, Montanini L, Mumm S, D'Urso M, Forabosco A. (literal)

Pagina inizio

• 61 (literal)

Pagina fine

• 67 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 8 (literal)

Rivista

• Human molecular genetics (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• [ 1 ] Univ Modena, Sez Istol Embriol & Genet, Dipartimento Sci Morfol & Medicolegali, I-41100 Modena, Italy Organization-Enhanced Name(s) University of Modena & Reggio Emilia [ 2 ] CNR, Int Inst Genet & Biophys, I-80125 Naples, Italy Organization-Enhanced Name(s) Consiglio Nazionale delle Ricerche (CNR) [ 3 ] Washington Univ, Sch Med, Div Bone & Mineral Dis, St Louis, MO 63110 USA (literal)

Titolo

• A novel pseudoautosomal human gene encodes a putative protein similar to Ac-like transposases (literal)

Abstract

• We report the cloning of a novel gene, called Tramp, in the Xp/Yp PAR region that has a functional homologue on the Y chromosome and escapes X-inactivation. This gene encodes, within a single exon, a putative protein that has amino acid similarity with transposases of the Ac family. Flanking this gene we have identified putative terminal inverted repeats (TIRs) and a duplicate target site, suggesting that it may be an ancient transposable element. The nucleotide differences in these sites and the TIR-binding inactivity of the putative Tramp protein suggest that this element is not an autonomous transposon. In the human genome, the Tramp protein may be involved in the transposition of other transposable elements, like medium reiterated frequency repeats, or it could be specialized in the acquisition of a new cellular function. (literal)

Prodotto di

• Istituto di genetica e biofisica \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Autore CNR

• TERESA ESPOSITO (Unità di personale interno)
• FERNANDO GIANFRANCESCO (Persona)
• ALFREDO CICCODICOLA (Persona)

Incoming links:

Autore CNR di

• FERNANDO GIANFRANCESCO (Persona)
• ALFREDO CICCODICOLA (Persona)
• TERESA ESPOSITO (Unità di personale interno)

Prodotto

• Istituto di genetica e biofisica \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Human molecular genetics (Rivista)