Dielectric properties of the plasma membrane of cultured murine fibroblasts treated with a nonterpenoid extract of Azadirachta indica seeds (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Dielectric properties of the plasma membrane of cultured murine fibroblasts treated with a nonterpenoid extract of Azadirachta indica seeds (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Alternative label

• Bonincontro, A; Di Ilio, V; Pedata, O; Risuleo, G (2007)
  Dielectric properties of the plasma membrane of cultured murine fibroblasts treated with a nonterpenoid extract of Azadirachta indica seeds
  
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Bonincontro, A; Di Ilio, V; Pedata, O; Risuleo, G (literal)

Pagina inizio

• 75 (literal)

Pagina fine

• 79 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 215 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Univ Roma La Sapienza, Dipartimento Genet & Biol Mol, I-00185 Rome, Italy; Univ Roma La Sapienza, Dipartimento Fis, CNISM, I-00185 Rome, Italy; Univ Roma La Sapienza, CNR Res Ctr, SOFT INFM, I-00185 Rome, Italy (literal)

Titolo

• Dielectric properties of the plasma membrane of cultured murine fibroblasts treated with a nonterpenoid extract of Azadirachta indica seeds (literal)

Abstract

• Neem oil is a natural product obtained from the seeds of the tree Azadirachta indica. In this report, we investigate the alterations of the biophysical properties of the plasma membrane caused by treatment with the nonterpenoid fraction of neem oil that we defined as methanolic extract (MEX). The dose-response effect was evaluated and a MEX-dependent cytoxicity evidenced. The effect of MEX on the plasma membrane was studied by a well-established dielectric spectroscopy technique: electrorotation, which allows single-cell analysis. Our results show a structural/functional alteration of the plasma membrane with an evident increase of specific capacitance and conductance. The biological implications of this effect are discussed. (literal)

Prodotto di

• Materia soffice: Self Assembly, Clustering, Arresto Strutturale (MD.P02.015.001) (Modulo)

Autore CNR

• GIANFRANCO RISULEO (Persona)
• ADALBERTO BONINCONTRO (Persona)

Insieme di parole chiave

• Keywords of "Dielectric properties of the plasma membrane of cultured murine fibroblasts treated with a nonterpenoid extract of Azadirachta indica seeds" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ADALBERTO BONINCONTRO (Persona)
• GIANFRANCO RISULEO (Persona)

Prodotto

• Materia soffice: Self Assembly, Clustering, Arresto Strutturale (MD.P02.015.001) (Modulo)

Insieme di parole chiave di

• Keywords of "Dielectric properties of the plasma membrane of cultured murine fibroblasts treated with a nonterpenoid extract of Azadirachta indica seeds" (Insieme di parole chiave)