http://www.cnr.it/ontology/cnr/individuo/prodotto/ID215740
In vitro tumour cell growth inhibition: a comparative study between allosensitized cytotoxic T lymphocytes and lymphokine activated killer cells. (Articolo in rivista)
- Type
- Label
- In vitro tumour cell growth inhibition: a comparative study between allosensitized cytotoxic T lymphocytes and lymphokine activated killer cells. (Articolo in rivista) (literal)
- Anno
- 1993-01-01T00:00:00+01:00 (literal)
- Alternative label
1)Fuggetta MP, 1)Alvino E, 1)Pepponi R, 2) De Filippi R, 3) Marini S, 1,2) Bonmassar E. (1993)
In vitro tumour cell growth inhibition: a comparative study between allosensitized cytotoxic T lymphocytes and lymphokine activated killer cells.
in Cell proliferation (Print)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- 1)Fuggetta MP, 1)Alvino E, 1)Pepponi R, 2) De Filippi R, 3) Marini S, 1,2) Bonmassar E. (literal)
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- Pagina fine
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- Rivista
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- PubMe (literal)
- Scopus (literal)
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Institute of Experimental Medicine, cnr , Rome, Italy
II University of Rome, Italy. (literal)
- Titolo
- In vitro tumour cell growth inhibition: a comparative study between allosensitized cytotoxic T lymphocytes and lymphokine activated killer cells. (literal)
- Abstract
- There is general agreement that several distinct subpopulation of lymphocytes, including major histocompatibility complex (MHC)-restricted T lymphocytes and non-restricted natural killer, or lymphokine-activated killer (LAK), cells are active in lysing neoplastic cells. In this study experiments were designed to compare the inhibitory effects of LAK cells and allosensitized cytotoxic T lymphocytes (CTL) on in vitro growth of an Epstein-Barr virus-transformed B-cell line (BSM) and of a HTLV-I producer T-cell line (MT-2). It was found that allosensitized CTL are more efficient at inducing BSM, or MT-2, cell growth inhibition than LAK cells. These results are consistent with the hypothesis that MHC-restricted T effector cells could mediate higher tumour suppressive effects than non-MHC restricted LAK cells. (literal)
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