Biochemical Composition, Antimicrobial Activities, and Anti-Quorum-Sensing Activities of Ethanol and Ethyl Acetate Extracts from Hypericum connatum Lam.(Guttiferae) (Articolo in rivista)

Type
Label
  • Biochemical Composition, Antimicrobial Activities, and Anti-Quorum-Sensing Activities of Ethanol and Ethyl Acetate Extracts from Hypericum connatum Lam.(Guttiferae) (Articolo in rivista) (literal)
Anno
  • 2013-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1089/jmf.2012.0197 (literal)
Alternative label
  • Florinda Fratianni, Filomena Nazzaro, Aurelio Marandino, Maria del Rosario Fusco, Raffaele Coppola, Vincenzo De Feo, Laura De Martino (2013)
    Biochemical Composition, Antimicrobial Activities, and Anti-Quorum-Sensing Activities of Ethanol and Ethyl Acetate Extracts from Hypericum connatum Lam.(Guttiferae)
    in Journal of medicinal food
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Florinda Fratianni, Filomena Nazzaro, Aurelio Marandino, Maria del Rosario Fusco, Raffaele Coppola, Vincenzo De Feo, Laura De Martino (literal)
Rivista
Note
  • Google S (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Fratianni, Coppola, Nazzaro: Istituto di Scienze dell'Alimentazione, ISA-CNR; Marandino, De Feo, De Martino: UNISA, Fisciano(SA); Fusco:Faculty of Chemistry, Biochemistry, and Pharmacy, National University of San Luis, San Luis, Argentina; (literal)
Titolo
  • Biochemical Composition, Antimicrobial Activities, and Anti-Quorum-Sensing Activities of Ethanol and Ethyl Acetate Extracts from Hypericum connatum Lam.(Guttiferae) (literal)
Abstract
  • We studied the polyphenol composition and antioxidant activity of the ethanolic and ethyl acetate extracts of Hypericum connatum(Guttiferae), in addition to their antimicrobial and antiquorum-sensing (AQS) properties. The extracts exhibited a similar polyphenol content and a notable antioxidant activity, which was stronger in the ethanolic extract (EC50=3.2 ?g/mL). Ultrahigh-performance liquid chromatography analyses revealed different polyphenol profiles, with rutin and apigen being the main components of the ethanolic extract and caffeic acid, (-)-epicatechin and p-coumaric acid being abundant in the ethyl acetate extract. The ethyl acetate extract exhibited a more effective antimicrobial activity than the ethanolic extract against the pathogens Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa. For the first time, AQS activity was detected in H. connatum: the ethanolic extract inhibited the production of violacein, a quorum-sensing-regulated pigment, in a Chromobacterium violaceum tester strain, without interfering with its growth. (literal)
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