Fertility and malarial polymorphisms in Sardinia. (Abstract/Poster in rivista)

Type
Label
  • Fertility and malarial polymorphisms in Sardinia. (Abstract/Poster in rivista) (literal)
Anno
  • 1991-01-01T00:00:00+01:00 (literal)
Alternative label
  • Astolfi P, Lisa A, Degioanni A, Zei G. (1991)
    Fertility and malarial polymorphisms in Sardinia.
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Astolfi P, Lisa A, Degioanni A, Zei G. (literal)
Pagina inizio
  • 465 (literal)
Pagina fine
  • 465 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 49 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 1 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 4 (literal)
Note
  • Poster (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • IGM-CNR; Università di Pavia (literal)
Titolo
  • Fertility and malarial polymorphisms in Sardinia. (literal)
Abstract
  • The hypothesis that fertility variation pay contribute in maintaining the balanced polymorphisms for malarial deleterious genes (beta-thalassaemia and G-6-P0 deficiency) in Sardinia was supported by a previous analysis in which differential fertility in areas with different incidence of malaria was found. The greater fertility rate in areas with wide incidence of malaria might be explained by a higher degree of acquired immunity and by a higher frequency of heterozygotes for malarial genes. Mow the direct relationship between fertility and frequency of heterozygotes for thalassaemia or G-6-PD deficiency is analysed. Demographic data come from 1961 Census and concern the fertility of 30,000 married women in postreproductive age, with the same socio cultural level, belonging to the 61 villages, for which genetic data were available. In the villages showing less frequency of heterozygoses the ntean number of children per fertile woman was found significantly lower and in the same villages the percent of sterile woman was higher than that of villages with high frequency of heterozygotes, The decrease in fertility that might be due to early foetal losses caused by plasmodlal infection of placenta, or less degree of acquired immunity, seemed to be confirmed by the higher mean age of the woman at the first child birth in the villages with lower frequency of heterozygotes. (literal)
Prodotto di
Autore CNR

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it