http://www.cnr.it/ontology/cnr/individuo/prodotto/ID20931
Nucleic acid aptamers in cancer medicine. (Articolo in rivista)
- Type
- Label
- Nucleic acid aptamers in cancer medicine. (Articolo in rivista) (literal)
- Anno
- 2002-01-01T00:00:00+01:00 (literal)
- Alternative label
Cerchia L. 1, Hamm J. 2, Libri D. 3, Tavitian B. 4, De Franciscis V. 1 (2002)
Nucleic acid aptamers in cancer medicine.
in FEBS letters (Print)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Cerchia L. 1, Hamm J. 2, Libri D. 3, Tavitian B. 4, De Franciscis V. 1 (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Note
- ISI Web of Science (WOS) (literal)
- Titolo
- Nucleic acid aptamers in cancer medicine. (literal)
- Abstract
- Many signalling proteins involved in diverse functions
such as cell growth and di¡erentiation can act as oncogenes
and cause cellular transformation. These molecules represent
attractive targets for cancer diagnosis or therapy and are
therefore subject to intensive investigation. Aptamers are small
nucleic acid molecules, isolated from combinatorial libraries by
a procedure termed SELEX, that bind to a target molecule by
providing a limited number of speci¢c contact points embedded
in a larger, de¢ned three-dimensional structure. In some cases
aptamers have the potential to inhibit the biological function of
the molecule resulting in useful reagents for target validation in
a variety of disease models. (literal)
- Prodotto di
- Autore CNR
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