y-Hemolysin oligomeric structure and effect of its formation on supported lipid bilayers: an AFM investigation (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• y-Hemolysin oligomeric structure and effect of its formation on supported lipid bilayers: an AFM investigation (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.bbamem.2012.09.027 (literal)

Alternative label

• Alessandrini A; Viero G; Dalla Serra M; Prévost G; Facci P (2013)
  y-Hemolysin oligomeric structure and effect of its formation on supported lipid bilayers: an AFM investigation
  in Biochimica et biophysica acta. Biomembranes
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Alessandrini A; Viero G; Dalla Serra M; Prévost G; Facci P (literal)

Pagina inizio

• 405 (literal)

Pagina fine

• 411 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/science/article/pii/S0005273612003483 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 1828 (literal)

Rivista

• Biochimica et biophysica acta. Biomembranes (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 2 (literal)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Centro S3, CNR-Istituto di Nanoscienze, Via Campi 213/A, 41125 Modena, Italy; Department of Physics, University of Modena and Reggio Emilia, Via Campi 213/A, 41125 Modena, Italy; CNR-Institute of Biophysics & Bruno Kessler Foundation, Via alla Cascata 56/C, 38123 Trento, Italy; UR EA Physiopathologie et Médecine Translationelle, Institut de Bactériologie de la faculté de médecine, 3 rue Koeberlé, 67000 Strasbourg, France (literal)

Titolo

• y-Hemolysin oligomeric structure and effect of its formation on supported lipid bilayers: an AFM investigation (literal)

Abstract

• y-Hemolysins are bicomponent ?-barrel pore forming toxins produced by Staphylococcus aureus as water-soluble monomers, which assemble into oligomeric pores on the surface of lipid bilayers. Here, after investigating the oligomeric structure of ?-hemolysins on supported lipid bilayers (SLBs) by atomic force microscopy (AFM), we studied the effect produced by this toxin on the structure of SLBs. We found that oligomeric structures with different number of monomers can assemble on the lipid bilayer being the octameric form the stablest one. Moreover, in this membrane model we found that ?-hemolysins can form clusters of oligomers inducing a curvature in the lipid bilayer, which could probably enhance the aggressiveness of these toxins at high concentrations. (literal)

Prodotto di

• Istituto di biofisica (IBF) (Istituto)
• Membrane biologiche, complessi macromolecolari e imaging biomolecolare (MD.P01.028.001) (Modulo)

Autore CNR

• MAURO DALLA SERRA (Unità di personale interno)
• GABRIELLA VIERO (Persona)

Insieme di parole chiave

• Parole chiave di "y-Hemolysin oligomeric structure and effect of its formation on supported lipid bilayers: an AFM investigation" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di biofisica (IBF) (Istituto)
• Membrane biologiche, complessi macromolecolari e imaging biomolecolare (MD.P01.028.001) (Modulo)

Autore CNR di

• MAURO DALLA SERRA (Unità di personale interno)
• GABRIELLA VIERO (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biochimica et biophysica acta. Biomembranes (Rivista)

Insieme di parole chiave di

• Parole chiave di "y-Hemolysin oligomeric structure and effect of its formation on supported lipid bilayers: an AFM investigation" (Insieme di parole chiave)