Identifying Correlations between Chromosomal Proximity of Genes and Distance of Their Products in Protein-Protein Interaction Networks of Yeast (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Identifying Correlations between Chromosomal Proximity of Genes and Distance of Their Products in Protein-Protein Interaction Networks of Yeast (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Alternative label

• Daniele santoni, Filippo Castiglione and Paola Paci (2013)
  Identifying Correlations between Chromosomal Proximity of Genes and Distance of Their Products in Protein-Protein Interaction Networks of Yeast
  in PloS one
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Daniele santoni, Filippo Castiglione and Paola Paci (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 8 (literal)

Rivista

• PloS one (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Daniele Santoni and Paola Paci - Institute for System Analysis and Computer Science \"Antonio Ruberti\", National Research Council of Italy, Rome, Italy. Filippo Castiglione - Institute for Computing Application \"Mauro Picone\", National Research Council of Italy, Rome, Italy. (literal)

Titolo

• Identifying Correlations between Chromosomal Proximity of Genes and Distance of Their Products in Protein-Protein Interaction Networks of Yeast (literal)

Abstract

• In this article we present evidence for a relationship between chromosome gene loci and the topological properties of the protein-protein interaction network corresponding to the set of genes under consideration. Specifically, for each chromosome of the Saccharomyces cerevisiae genome, the distribution of the intra-chromosome inter-gene distances was analyzed and a positive correlation with the distance among the corresponding proteins of the protein-protein interaction network was found. In order to study this relationship we used concepts based on non-parametric statistics and information theory. We provide statistical evidence that if two genes are closely located, then it is likely that their protein products are closely located in the protein-protein interaction network, or in other words, that they are involved in the same biological process. (literal)

Prodotto di

• Modellizzazione quantitativa di sistemi biologici complessi (SV.P18.002.001) (Modulo)
• Ottimizzazione e modellistica matematica in biologia (INT.P02.003.001) (Modulo)
• Istituto di analisi dei sistemi ed informatica \"Antonio Ruberti\" (IASI) (Istituto)
• Istituto per le applicazioni del calcolo \"Mauro Picone\" (IAC) (Istituto)

Autore CNR

• DANIELE SANTONI (Unità di personale interno)
• PAOLA PACI (Unità di personale interno)
• FILIPPO CASTIGLIONE (Persona)

Incoming links:

Prodotto

• Istituto per le applicazioni del calcolo \"Mauro Picone\" (IAC) (Istituto)
• Istituto di analisi dei sistemi ed informatica \"Antonio Ruberti\" (IASI) (Istituto)
• Modellizzazione quantitativa di sistemi biologici complessi (SV.P18.002.001) (Modulo)
• Ottimizzazione e modellistica matematica in biologia (INT.P02.003.001) (Modulo)

Autore CNR di

• FILIPPO CASTIGLIONE (Persona)
• PAOLA PACI (Unità di personale interno)
• DANIELE SANTONI (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• PloS one (Rivista)