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Elastomeric nanocomposite based on Carbon Nanotubes for Polymerase Chain Reaction device (Articolo in rivista)

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Elastomeric nanocomposite based on Carbon Nanotubes for Polymerase Chain Reaction device (Articolo in rivista) (literal)

Anno

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Alternative label

Quaglio, M. 1, Bianco, S. 1, Castagna, R. 2, Cocuzza, M. 2,3, Pirri, C. F. 1,2 (2011)
Elastomeric nanocomposite based on Carbon Nanotubes for Polymerase Chain Reaction device
in Microelectronic engineering; Elsevier, Amsterdam (Paesi Bassi); ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, AMSTERDAM (Paesi Bassi)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Quaglio, M. 1, Bianco, S. 1, Castagna, R. 2, Cocuzza, M. 2,3, Pirri, C. F. 1,2 (literal)

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Proceedings of the 36th International Conference on Micro- and Nano-Engineering (MNE), 36th International Conference on Micro- and Nano-Engineering (MNE) ID_PUMA: cnr.imem/2011-A0-022 (literal)

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Note

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[ 1 ] Fdn Ist Italian Tecnol, Ctr Space Human Robot, I-10129 Turin, Italy; [ 2 ] Politecn Torino, Mat & Microsyst Lab Chilab, Latemar Unit, Mat Sci & Chem Engn Dept, I-10129 Turin, Italy; [ 3 ] CNR IMEM, I-43124 Parma, Italy (literal)

Titolo

Elastomeric nanocomposite based on Carbon Nanotubes for Polymerase Chain Reaction device (literal)

Abstract

The low thermal conductivity of polymers is the main problem to design efficient disposable polymeric Polymerase Chain Reaction (PCR) devices. The introduction of nanocomposite (NC) materials to fabricate Lab-On-a-Chips (LOCs) for on-chip PCR can improve the thermal response of the final device, fastening the PCR thermocycling. In this study, we propose the application of the nanocomposite obtained introducing Multi-Walled Carbon NanoTubes (MWCNTs) into Poly(DiMethyl)Siloxane (PDMS). We demonstrate a better thermal behavior for devices made of the nanocomposite material, observing faster transitions and a better control in steady-state temperatures. The better thermal performance of the nanocomposite-based device is mirrored by an efficiency increase in PCR reaction, demonstrating the direct enhancing effect of the CNTs content in the composite. This novel approach allows us to reach a more precise control in the biological reaction, with a beneficial effect on process efficiency, actually introducing a new class of devices. (literal)

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