Challenges in the accurate speciation analysis of selenium in humans: first report on indicative levels of selenoproteins in a serum certified reference material for total selenium (BCR-637) (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Challenges in the accurate speciation analysis of selenium in humans: first report on indicative levels of selenoproteins in a serum certified reference material for total selenium (BCR-637) (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Alternative label

• Jitaru P., Roman M., Barbante C., Vaslin-Reimann S., Fisicaro P. (2010)
  Challenges in the accurate speciation analysis of selenium in humans: first report on indicative levels of selenoproteins in a serum certified reference material for total selenium (BCR-637)
  in Accreditation and quality assurance
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Jitaru P., Roman M., Barbante C., Vaslin-Reimann S., Fisicaro P. (literal)

Pagina inizio

• 343 (literal)

Pagina fine

• 350 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 15 (literal)

Rivista

• Accreditation and quality assurance (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• Challenges in the accurate speciation analysis of selenium in humans: first report on indicative levels of selenoproteins in a serum certified reference material for total selenium (BCR-637) (literal)

Abstract

• Se is one of the most investigated essential trace elements in the past years, mostly due to its cancer prevention properties. Nevertheless, the accurate determination of its biologically active species, such as the selenoproteins (SeProt) in human serum, is currently a challenging task. This is because of the lack of appropriate quantification standards, certified reference materials (CRMs), and/or reference measurement methods. Additionally, most of the methods developed so far for the determination of SeProt were applied to the analysis of control (volunteers) serums, which are not available to other laboratories, therefore making methods inter-comparison virtually impossible. We present here for the first time indicative levels of SeProt in a commercially available human serum, namely the BCR-637 CRM with certified level of total Se. The concentrations of selenium associated with glutathione peroxidase (GPx), selenoprotein P (SelP) and selenoalbumin (SeAlb) in this serum were calculated using the results obtained by 13 different analytical methods (literature and non-published data) on the basis of (affinity) high-performance liquid chromatography (AF-HPLC) coupled to inductively coupled plasma-mass spectrometry (ICP-MS). The indicative levels of SeProt in the BCR-637 serum can be used for validation of methods dealing with the determination of these proteins in human serum. (literal)

Prodotto di

• Istituto per la dinamica dei processi ambientali (IDPA) (Istituto)
• Microinquinanti organici ed inorganici in aree a diversa antropizzazione (TA.P03.011.001) (Modulo)

Autore CNR

• MARCO ROMAN (Unità di personale esterno)
• PETRU JITARU (Unità di personale esterno)
• CARLO BARBANTE (Persona)

Insieme di parole chiave

• Parole chiave di "Challenges in the accurate speciation analysis of selenium in humans: first report on indicative levels of selenoproteins in a serum certified reference material for total selenium (BCR-637)" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto per la dinamica dei processi ambientali (IDPA) (Istituto)
• Microinquinanti organici ed inorganici in aree a diversa antropizzazione (TA.P03.011.001) (Modulo)

Autore CNR di

• PETRU JITARU (Unità di personale esterno)
• CARLO BARBANTE (Persona)
• MARCO ROMAN (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Accreditation and quality assurance (Rivista)

Insieme di parole chiave di

• Parole chiave di "Challenges in the accurate speciation analysis of selenium in humans: first report on indicative levels of selenoproteins in a serum certified reference material for total selenium (BCR-637)" (Insieme di parole chiave)