Conjoined Twins: A Worldwide Collaborative Epidemiological Study of the International Clearinghouse for Birth Defects Surveillance and Research (Articolo in rivista)

Type
Label
  • Conjoined Twins: A Worldwide Collaborative Epidemiological Study of the International Clearinghouse for Birth Defects Surveillance and Research (Articolo in rivista) (literal)
Anno
  • 2011-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1002/ajmg.c.30321 (literal)
Alternative label
  • Mutchinick, OM (Mutchinick, Osvaldo M.)[ 1 ] ; Luna-Munoz, L (Luna-Munoz, Leonora)[ 1 ] ; Amar, E (Amar, Emmanuelle)[ 2 ] ; Bakker, MK (Bakker, Marian K.)[ 3 ] ; Clementi, M (Clementi, Maurizio)[ 4 ] ; Cocchi, G (Cocchi, Guido)[ 5 ] ; Dutra, MD (Dutra, Maria da Graca)[ 6,7 ] ; Feldkamp, ML (Feldkamp, Marcia L.)[ 8,9 ] ; Landau, D (Landau, Danielle)[ 10 ] ; Leoncini, E (Leoncini, Emanuele)[ 11 ] ; Li, Z (Li, Zhu)[ 12 ] ; Lowry, B (Lowry, Brian)[ 13 ] ; Marengo, LK (Marengo, Lisa K.)[ 14 ] ; Martinez-Frias, ML (Martinez-Frias, Maria-Luisa)[ 15,16,17 ] ; Mastroiacovo, P (Mastroiacovo, Pierpaolo)[ 11 ] ; Metneki, J (Metneki, Julia)[ 18 ] ; Morgan, M (Morgan, Margery)[ 19 ] ; Pierini, A (Pierini, Anna)[ 20 ] ; Rissman, A (Rissman, Anke)[ 21 ] ; Ritvanen, A (Ritvanen, Annukka)[ 22 ] ; Scarano, G (Scarano, Gioacchino)[ 23 ] ; Siffel, C (Siffel, Csaba)[ 24 ] ; Szabova, E (Szabova, Elena)[ 25 ] ; Arteaga-Vazquez, J (Arteaga-Vazquez, Jazmin)[ 1 ] (2011)
    Conjoined Twins: A Worldwide Collaborative Epidemiological Study of the International Clearinghouse for Birth Defects Surveillance and Research
    in American journal of medical genetics. Part C, Seminars in medical genetics
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Mutchinick, OM (Mutchinick, Osvaldo M.)[ 1 ] ; Luna-Munoz, L (Luna-Munoz, Leonora)[ 1 ] ; Amar, E (Amar, Emmanuelle)[ 2 ] ; Bakker, MK (Bakker, Marian K.)[ 3 ] ; Clementi, M (Clementi, Maurizio)[ 4 ] ; Cocchi, G (Cocchi, Guido)[ 5 ] ; Dutra, MD (Dutra, Maria da Graca)[ 6,7 ] ; Feldkamp, ML (Feldkamp, Marcia L.)[ 8,9 ] ; Landau, D (Landau, Danielle)[ 10 ] ; Leoncini, E (Leoncini, Emanuele)[ 11 ] ; Li, Z (Li, Zhu)[ 12 ] ; Lowry, B (Lowry, Brian)[ 13 ] ; Marengo, LK (Marengo, Lisa K.)[ 14 ] ; Martinez-Frias, ML (Martinez-Frias, Maria-Luisa)[ 15,16,17 ] ; Mastroiacovo, P (Mastroiacovo, Pierpaolo)[ 11 ] ; Metneki, J (Metneki, Julia)[ 18 ] ; Morgan, M (Morgan, Margery)[ 19 ] ; Pierini, A (Pierini, Anna)[ 20 ] ; Rissman, A (Rissman, Anke)[ 21 ] ; Ritvanen, A (Ritvanen, Annukka)[ 22 ] ; Scarano, G (Scarano, Gioacchino)[ 23 ] ; Siffel, C (Siffel, Csaba)[ 24 ] ; Szabova, E (Szabova, Elena)[ 25 ] ; Arteaga-Vazquez, J (Arteaga-Vazquez, Jazmin)[ 1 ] (literal)
Pagina inizio
  • 274 (literal)
Pagina fine
  • 287 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 157 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 14 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 4 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • [ 1 ] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Genet, RYVEMCE, Mexico City 14000, DF, Mexico [ 2 ] Rhone Alps Registry Birth Defects REMERA, Lyon, France [ 3 ] Univ Groningen, Univ Med Ctr Groningen, Dept Genet, NL-9713 AV Groningen, Netherlands [ 4 ] Univ Padua, Dept Pediat, Clin Genet Unit, Padua, Italy [ 5 ] Univ Bologna, Dept Pediat, IMER Registry, Bologna, Italy [ 6 ] INAGEMP Inst Nacl Genet Med Populac Rio de Janeir, Rio De Janeiro, Brazil [ 7 ] Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, ECLAMC, Rio De Janeiro, Brazil [ 8 ] Univ Utah Hlth Sci Ctr, Dept Med Genet, Salt Lake City, UT USA [ 9 ] Utah Dept Hlth, Utah Birth Defect Network, Salt Lake City, UT 84116 USA [ 10 ] Soroka Univ Med Ctr, Dept Neonatol, Beer Sheva, Israel [ 11 ] Ctr Int Clearinghouse Birth Defects Surveillance, Rome, Italy [ 12 ] Peking Univ Hlth Sci Ctr, Natl Ctr Maternal & Infant Hlth, Beijing, Peoples R China [ 13 ] Alberta Hlth & Wellness, Alberta Congenital Anomalies Surveillance Syst, Calgary, AB, Canada [ 14 ] Texas Dept State Hlth Serv, Birth Defects Epidemiol & Surveillance Branch, Austin, TX USA [ 15 ] ISCIII, CIAC, ECEMC Spanish Collaborat Study Congenital Malform, Madrid, Spain [ 16 ] Ctr Biomed Res Rare Dis, CIBERER, Madrid, Spain [ 17 ] Univ Complutense Madrid, Fac Med, Dept Pharmacol, E-28040 Madrid, Spain [ 18 ] Natl Ctr Healthcare Audit & Inspect, Dept Hungarian Congenital Abnormal Registry & Sur, Budapest, Hungary [ 19 ] Singleton Hosp, CARIS, Swansea SA2 8QA, W Glam, Wales [ 20 ] Inst Clin Fisiol, CNR, Epidemiol Unit, RTDC, Pisa, Italy [ 21 ] Malformat Monitoring Ctr Saxony Anhalt, Magdeburg, Germany [ 22 ] THL, Natl Inst Hlth & Welf, Helsinki, Finland [ 23 ] Gen Hosp G Rummo Benevento, Dept Med Genet, Birth Defects Campania Registry, Benevento, Italy [ 24 ] Ctr Dis Control & Prevent, Metropolitan Atlanta Congenital Defects Program, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA [ 25 ] Slovak Med Univ, Slovak Teratol Informat Ctr, Bratislava, Slovakia (literal)
Titolo
  • Conjoined Twins: A Worldwide Collaborative Epidemiological Study of the International Clearinghouse for Birth Defects Surveillance and Research (literal)
Abstract
  • Conjoined twins (CT) are a very rare developmental accident of uncertain etiology. Prevalence has been previously estimated to be 1 in 50,000 to 1 in 100,000 births. The process by which monozygotic twins do not fully separate but form CT is not well understood. The purpose of the present study was to analyze diverse epidemiological aspects of CT, including the different variables listed in the Introduction Section of this issue of the Journal. The study was made possible using the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR) structure. This multicenter worldwide research includes the largest sample of CT ever studied. A total of 383 carefully reviewed sets of CT obtained from 26,138,837 births reported by 21 Clearinghouse Surveillance Programs (SP) were included in the analysis. Total prevalence was 1.47 per 100,000 births (95% CI: 1.32-1.62). Salient findings including an evident variation in prevalence among SPs: a marked variation in the type of pregnancy outcome, a similarity in the proportion of CT types among programs: a significant female predominance in CT: particularly of the thoracopagus type and a significant male predominance in parapagus and parasitic types: significant differences in prevalence by ethnicity and an apparent increasing prevalence trend in South American countries. No genetic, environmental or demographic significant associated factors were identified. Further work in epidemiology and molecular research is necessary to understand the etiology and pathogenesis involved in the development of this fascinating phenomenon of nature (literal)
Prodotto di
Autore CNR

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it