Simultaneous determination of human pharmaceuticals in water samples by solid phase extraction and HPLC with UV-fluorescence detection (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Simultaneous determination of human pharmaceuticals in water samples by solid phase extraction and HPLC with UV-fluorescence detection (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Alternative label

• Patrolecco L., Ademollo N., Grenni P., Tolomei A., Barra Caracciolo A., Capri S. (2013)
  Simultaneous determination of human pharmaceuticals in water samples by solid phase extraction and HPLC with UV-fluorescence detection
  in Microchemical journal (Print); Elsevier B.V., Amsterdam (Belgio)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Patrolecco L., Ademollo N., Grenni P., Tolomei A., Barra Caracciolo A., Capri S. (literal)

Pagina inizio

• 165 (literal)

Pagina fine

• 171 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 107 (literal)

Rivista

• Microchemical journal (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Istituto di Ricerca sulle Acque, Roma (literal)

Titolo

• Simultaneous determination of human pharmaceuticals in water samples by solid phase extraction and HPLC with UV-fluorescence detection (literal)

Abstract

• The presence of pharmaceutical active products (PPs) in the aquatic environment is principally due to insufficient removal at wastewater treatment plants (WWTPs). Although PPs and their metabolites are often found in waters at trace levels, they can maintain a high biological activity with potential adverse effects on biotic communities. The development of accurate and sensitive methods is therefore necessary for their detection in aquatic ecosystems. In this context, the aim of this study was to validate a simple and reliable analytical procedure for determining selected pharmaceuticals in wastewaters and surface waters by applying solid phase extraction (SPE) using polymeric Strata X extraction cartridges and HPLC with simultaneous UV and fluorescence detection. Nine selected PPs belonging to different therapeutic classes (carbamazepine, gemfibrozil, clofibric acid, fenofibrate, fenoprofen, ibuprofen, naproxen, ketoprofen, and diclofenac) and three steroid hormones (17?-estradiol, 17?-ethinylestradiol, and estrone)were considered. Themethod, validated on spiked real water samples (river water, influent and effluent from a WWTP), showed satisfactory accuracy and sensitivity, with average recoveries in the 65-104% range and relative standard deviations (RSD)<=16%. The limits of quantification (LOQs) ranged from 10 to 1100 ng/L for all spiked matrices. The optimized method has been successfully applied to the detection of the selected compounds in environmental waters, such as two contaminated sites along the urban stretch of the River Tiber in the city of Rome (Italy) and from both the influent and effluent from a municipalWWTP close to Rome. The method developed is proposed for routine analysis of PPs in polluted waters as it is a useful and affordable alternative when more sophisticated techniques are not available. (literal)

Editore

• Elsevier B.V. (Editore)

Prodotto di

• Diffusione, ripartizione, bioaccumulo e trasformazione di inquinanti in ecosistemi acquatici (TA.P04.021.007) (Modulo)
• Water research institute (IRSA) (Istituto)

Autore CNR

• NICOLETTA ADEMOLLO (Unità di personale esterno)
• LUISA PATROLECCO (Unità di personale interno)
• SILVIO CAPRI (Unità di personale interno)
• PAOLA GRENNI (Unità di personale interno)
• ANNA BARRA CARACCIOLO (Persona)

Insieme di parole chiave

• Keywords of "Simultaneous determination of human pharmaceuticals in water samples by solid phase extraction and HPLC with UV-fluorescence detection" (Insieme di parole chiave)

Incoming links:

Prodotto

• Water research institute (IRSA) (Istituto)
• Diffusione, ripartizione, bioaccumulo e trasformazione di inquinanti in ecosistemi acquatici (TA.P04.021.007) (Modulo)

Autore CNR di

• NICOLETTA ADEMOLLO (Unità di personale esterno)
• ANNA BARRA CARACCIOLO (Persona)
• LUISA PATROLECCO (Unità di personale interno)
• PAOLA GRENNI (Unità di personale interno)
• SILVIO CAPRI (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Microchemical journal (Rivista)

Editore di

• Elsevier B.V. (Editore)

Insieme di parole chiave di

• Keywords of "Simultaneous determination of human pharmaceuticals in water samples by solid phase extraction and HPLC with UV-fluorescence detection" (Insieme di parole chiave)