http://www.cnr.it/ontology/cnr/individuo/prodotto/ID200058
In vivo laser assisted end-to-end anastomosis with ICG-infused chitosan patches (Contributo in atti di convegno)
- Type
- Label
- In vivo laser assisted end-to-end anastomosis with ICG-infused chitosan patches (Contributo in atti di convegno) (literal)
- Anno
- 2011-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1117/12.889800 (literal)
- Alternative label
Rossi F, Matteini P, Esposito G, Scerrati A, Albanese A, Puca A, Maira G, Rossi G, Pini R (2011)
In vivo laser assisted end-to-end anastomosis with ICG-infused chitosan patches
in Medical Laser Applications and Laser-Tissue Interactions V - Proceedings of SPIE, Munich, 24 May 2011
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Rossi F, Matteini P, Esposito G, Scerrati A, Albanese A, Puca A, Maira G, Rossi G, Pini R (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
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- ISI Web of Science (WOS) (literal)
- Scopu (literal)
- Google Scholar (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Institute of Applied Physics Nello Carrara, CNR, Sesto F.no (Florence), Italy
Institute of Neurosurgery, Catholic University, Roma, Italy
Department of Veterinary Sciences, University of Camerino, Matelica (MC), Italy (literal)
- Titolo
- In vivo laser assisted end-to-end anastomosis with ICG-infused chitosan patches (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
- Abstract
- Laser assisted vascular repair is a new optimized technique based on the use of ICG-infused chitosan patch to close a vessel wound, with or even without few supporting single stitches. We present an in vivo experimental study on an innovative end-to-end laser assisted vascular anastomotic (LAVA) technique, performed with the application of ICG-infused chitosan patches. The photostability and the mechanical properties of ICG-infused chitosan films were preliminary measured. The in vivo study was performed in 10 New Zealand rabbits. After anesthesia, a 3-cm segment of the right common carotid artery was exposed, thus clamped proximally and distally. The artery was then interrupted by means of a full thickness cut. Three single microsutures were used to approximate the two vessel edges. The ICG-infused chitosan patch was rolled all over the anastomotic site and welded by the use of a diode laser emitting at 810 nm and equipped with a 300 mu m diameter optical fiber. Welding was obtained by delivering single laser spots to induce local patch/tissue adhesion. The result was an immediate closure of the anastomosis, with no bleeding at clamps release. Thus animals underwent different follow-up periods, in order to evaluate the welded vessels over time. At follow-up examinations, all the anastomoses were patent and no bleeding signs were documented. Samples of welded vessels underwent histological examinations. Results showed that this technique offer several advantages over conventional suturing methods: simplification of the surgical procedure, shortening of the operative time, better re-endothelization and optimal vascular healing process (literal)
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