http://www.cnr.it/ontology/cnr/individuo/prodotto/ID198493
The ubiquitin/26S proteasome pathway in the integration of developmental signals at the plant shoot apical meristem (Abstract/Poster in convegno)
- Type
- Label
- The ubiquitin/26S proteasome pathway in the integration of developmental signals at the plant shoot apical meristem (Abstract/Poster in convegno) (literal)
- Anno
- 2012-01-01T00:00:00+01:00 (literal)
- Alternative label
DI GIACOMO E, IANNELLI MA, IAFRATE S, SERINO G, QU L-J, XIE Q, FRUGIS G (2012)
The ubiquitin/26S proteasome pathway in the integration of developmental signals at the plant shoot apical meristem
in Congresso della Federazione Italiana di Scienze della Vita (FISV) 2012, Roma, 24-27 Settembre 2012
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- DI GIACOMO E, IANNELLI MA, IAFRATE S, SERINO G, QU L-J, XIE Q, FRUGIS G (literal)
- Note
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- DGE, IMA, IS, FG: Istituto di Biologia e Biotecnologia Agraria (IBBA), Operative Unit of Rome, Consiglio Nazionale delle Ricerche (CNR), Via Salaria Km. 29,300, 00015 Monterotondo Scalo (Roma, Italia)
SG: Dipartimento di Genetica e Biologia Molecolare, University La Sapienza of Rome, P.le Aldo Moro 5, 00185 Roma (Italia)
QLJ:Peking-Yale Joint Center for Plant Molecular Genetics and AgroBiotechnology Peking University, Beijing 100871 (China)
XQ: Institute of Genetics and Developmental Biology, Chinese Academy of Sciences No.1 West Beichen Road, Beijing 100101 (China) (literal)
- Titolo
- The ubiquitin/26S proteasome pathway in the integration of developmental signals at the plant shoot apical meristem (literal)
- Abstract
- Ubiquitin-mediated degradation of regulatory proteins controls key events in plant development and response to the environment. Within the framework of a Scientific and Technological Cooperation between Italy and China (MAE-MIUR) we are investigating the involvement of ubiquitin-mediated proteolysis in the integration of developmental and environmental signals exerted by Knotted1-like homeobox (KNOX) and NAM/ATAF/CUC (NAC) domain transcription factors at the plant shoot apex. KNOXs and NACs play a key role in establishing the fine equilibrium between cell differentiation and stem cell maintenance in the shoot apical meristem (SAM), a population of undifferentiated cells at the tip of the shoot axis that establishes early during plant embryogenesis and gives rise to all shoot organs throughout the plant's life.
We produced transgenic Arabidopsis lines with constitutive or inducible alteration of the activity of a generic E2 UPS component and analyzed the effect on SAM function. In silico gene expression analysis and protein-protein interaction studies identified E2 and E3 enzymes putatively involved in the developmental pathways controlled by KNOX and NAC transcription factors. (literal)
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