An Innovative Plastic Optical Fiber-based Biosensor for new Bio/applications. The Case of Celiac Disease (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• An Innovative Plastic Optical Fiber-based Biosensor for new Bio/applications. The Case of Celiac Disease (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.snb.2012.10.055 (literal)

Alternative label

• CENNAMO N., VARRIALE A., PENNACCHIO A., STAIANO M., MASSAROTTI D., ZENI L., D'AURIA S. (2013)
  An Innovative Plastic Optical Fiber-based Biosensor for new Bio/applications. The Case of Celiac Disease
  in Sensors and actuators. B, Chemical (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• CENNAMO N., VARRIALE A., PENNACCHIO A., STAIANO M., MASSAROTTI D., ZENI L., D'AURIA S. (literal)

Pagina inizio

• 1008 (literal)

Pagina fine

• -1014 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/science/article/pii/S0925400512010799 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 176 (literal)

Rivista

• Sensors and actuators. B, Chemical (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• a Second University of Naples, Department of Information Engineering, Via Roma 29, 81031 Aversa, Italy b Laboratory for Molecular Sensing, IBP-CNR, Via Pietro Castellino 111, 80131 Napoli, Italy c University of Naples \"Federico II\", Department of Physical Sciences, Via Cinthia, Naples, Italy (literal)

Titolo

• An Innovative Plastic Optical Fiber-based Biosensor for new Bio/applications. The Case of Celiac Disease (literal)

Abstract

• In this work an innovative and low cost surface plasmon resonance (SPR) biosensor, based on the utilization of plastic optical fibers (POF), is presented and experimentally tested for the diagnosis and/or follow-up of celiac disease. In particular, the POF-based sensor was used to monitor the formation of the transglutaminase/anti-transglutaminase antibodies formation, a new hallmark for the diagnosis of celiac disease. In particular, on the gold layer surface of the POF sensor, the guinea pig transglutaminase was immobilized. The ability of the POF-sensor to detect the binding of anti-transglutaminase antibodies to the immobilized transglutaminase was studied. The obtained results showed that the POF-sensor is able to sense the transglutaminase/anti-transglutaminase complex in the range of concentrations between 30 nM and 3000 nM. Importantly, the proposed sensing method could be easily expanded to different target compounds. (literal)

Prodotto di

• DR. D'AURIA: Progettazione e Sviluppo di Biochip per la Sicurezza Alimentare e Salute Umana (AG.P05.001.001) (Modulo)
• Institute of protein biochemistry (IBP) (Istituto)

Autore CNR

• SABATO D'AURIA (Persona)
• MARIA STAIANO (Persona)
• ANTONIO VARRIALE (Persona)
• ANGELA PENNACCHIO (Unità di personale esterno)

Insieme di parole chiave

• Keywords of "An Innovative Plastic Optical Fiber-based Biosensor for new Bio/applications. The Case of Celiac Disease" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• SABATO D'AURIA (Persona)
• MARIA STAIANO (Persona)
• ANTONIO VARRIALE (Persona)
• ANGELA PENNACCHIO (Unità di personale esterno)

Prodotto

• Institute of protein biochemistry (IBP) (Istituto)
• DR. D'AURIA: Progettazione e Sviluppo di Biochip per la Sicurezza Alimentare e Salute Umana (AG.P05.001.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Sensors and actuators. B, Chemical (Rivista)

Insieme di parole chiave di

• Keywords of "An Innovative Plastic Optical Fiber-based Biosensor for new Bio/applications. The Case of Celiac Disease" (Insieme di parole chiave)