Characterisation of a label-free biosensor based on long period grating (Articolo in rivista)

Type
Label
  • Characterisation of a label-free biosensor based on long period grating (Articolo in rivista) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1002/jbio.201200135 (literal)
Alternative label
  • F.Chiavaioli, C.Trono, A.Giannetti, M.Brenci, F.Baldini (2014)
    Characterisation of a label-free biosensor based on long period grating
    in Journal of biophotonics (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • F.Chiavaioli, C.Trono, A.Giannetti, M.Brenci, F.Baldini (literal)
Pagina inizio
  • 1 (literal)
Pagina fine
  • 11 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 5 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 11 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 2 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • IFAC-CNR, Sesto Fiorentino, Firenze (literal)
Titolo
  • Characterisation of a label-free biosensor based on long period grating (literal)
Abstract
  • Optical fibre gratings, especially long period gratings, have been recently proposed as optical devices for biochemical sensing. A biochemical interaction along the grating portion induces a refractive index change and hence a change in the fiber transmission spectrum. This provides an alternative methodology with respect to other label-free optical approaches, such as surface plasmon resonance, interferometric configurations and optical resonators. The fibre biofunctionalization has been carried out by means of a novel chemistry using Eudragit L100 copolymer as opposed to the commonly used silanization procedure. Antigen-antibody interaction has been analysed by means of an IgG/anti-IgG bioassay. The biosensor was fully characterised, monitoring the kinetics during the antibody immobilization and the antigen interaction and achieving the calibration curve of the assay. A comparison of the biosensor performance was made by using two different long period gratings with distinct periods. Sketch of the proposed biosensor based on a long period grating. After the deposition of the biolayer, the interaction between the coupled cladding mode and the surrounding environment causes a refractive index change of the layer. The enlargement details the composition of the biolayer. (literal)
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it