http://www.cnr.it/ontology/cnr/individuo/prodotto/ID19712
Question: What is the biological function of the polyamines? (Articolo in rivista)
- Type
- Label
- Question: What is the biological function of the polyamines? (Articolo in rivista) (literal)
- Anno
- 2004-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1080/15216540410001673996 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Rea G., Bocedi A., Cervelli M. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
- http://onlinelibrary.wiley.com (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- PubMe (literal)
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Rea G. -IC-CNR, Roma
Bocedi A. -National Institute for Infectious Diseases I.R.C.C.S. Lazzaro Spallanzani, Roma
Cervelli M. -Dipartimento di Biologia, UniversitàRoma Tre, Roma (literal)
- Titolo
- Question: What is the biological function of the polyamines? (literal)
- Abstract
- All living organisms employ a complex array of regulatory
mechanisms to hold constant the intracellular polyamine (PA)
pool size. Putrescine, cadaverine, spermidine and spermine are
biologically ubiquitous alkylamines bearing, at physiological
pH values, positive charge on their primary and secondary
amino groups. PAs are considered to be universal cellular
regulators and can be found in free or conjugated forms (1).
As polycations they interact with negatively-charged DNA,
RNA, proteins, phospholipids, and nucleoside triphosphates.
Far from behaving merely as cations, PAs can also participate
in hydrophobic interactions through their methylene bridging
groups. Variations among different PAs, in the number and in
the distance of amino groups, provide for their functional
specificity (literal)
- Prodotto di
- Autore CNR
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