http://www.cnr.it/ontology/cnr/individuo/prodotto/ID197079
The effect of diterpenoidic diacylglycerols on tentacle regeneration in Hydra vulgaris. (Articolo in rivista)
- Type
- Label
- The effect of diterpenoidic diacylglycerols on tentacle regeneration in Hydra vulgaris. (Articolo in rivista) (literal)
- Anno
- 1991-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/0742-8413(91)90047-W (literal)
- Alternative label
De Petrocellis L, Di Marzo V, Arcà B, Gavagnin M, Minei R, Cimino G. (1991)
The effect of diterpenoidic diacylglycerols on tentacle regeneration in Hydra vulgaris.
in Comparative biochemistry and physiology. C. Comparative pharmacology and toxicology; Pergamon-Elsevier Science Ltd., Oxford (Regno Unito)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- De Petrocellis L, Di Marzo V, Arcà B, Gavagnin M, Minei R, Cimino G. (literal)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1. CNR, IST CIBERNETICA, VIA TOIANO 6, I-80072 ARCO FELICE, ITALY.
2. CNR, IST CHIM MOLEC INTERESSE BIOL, I-80072 ARCO FELICE, ITALY (literal)
- Titolo
- The effect of diterpenoidic diacylglycerols on tentacle regeneration in Hydra vulgaris. (literal)
- Abstract
- 1. The effect of two ichthyotoxic diterpenoid diacylglycerols, verrucosins A and B, previously isolated from the mantle of a marine nudibranch mollusc, were studied on Hydra vulgaris tentacle regeneration.
2. A potent effect was found for both verrucosins in the low nanomolar range; the rank of potency observed was analogous to that reported for diglycerid activation of protein kinase C and to that found for verrucosin activation of this enzyme.
3. In the high nanomolar range, the two verrucosins were found to be toxic to Hydra vulgaris.
4. Verrucosin B-induced toxicity and tentacle regeneration were found to be dependent on [Ca2+] in the assay medium. (literal)
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