Development of a gold-nanostructured surface for amperometric genosensors (Articolo in rivista)

Type
Label
  • Development of a gold-nanostructured surface for amperometric genosensors (Articolo in rivista) (literal)
Anno
  • 2012-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1007/s11051-012-1148-2 (literal)
Alternative label
  • Zanardi, C; Baldoli, C; Licandro, E; Terzi, F; Seeber, R. (2012)
    Development of a gold-nanostructured surface for amperometric genosensors
    in Journal of nanoparticle research; SPRINGER, DORDRECHT (Paesi Bassi)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Zanardi, C; Baldoli, C; Licandro, E; Terzi, F; Seeber, R. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 14 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 10 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Univ Modena & Reggio Emilia, Dipartimento Chim, Modena, Italy CNR, Ist Sci & Tecnol Mol, I-20133 Milan, Italy Univ Milan, Dipartimento Chim Organ & Ind, Milan, Italy (literal)
Titolo
  • Development of a gold-nanostructured surface for amperometric genosensors (literal)
Abstract
  • A gold-nanostructured surface has been obtained by stable deposition of chemically synthesized gold nanoparticles (2.1-5.5 nm size range) on a gold substrate through a dithiol linker. The method proposed for the obtainment of the nanostructure is suitable for the further stable anchoring of a peptide nucleic acid oligomer through four amine groups of lysine terminal residues, leading to fairly reproducible systems. The geometric area of the nanostructured surface is compared with those of a smooth and of an electrochemically generated nanostructured surface by depositing a probe bearing an electrochemically active ferrocene residue. Despite the area of the two nanostructures being quite similar, the response toward a 2 nM target oligonucleotide sequence is particularly high when using the surface built up by nanoparticle deposition. This aspect indicates that morphologic details of the nanostructure play a key role in conditioning the performances of the genosensors. (literal)
Editore
Prodotto di
Autore CNR

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Editore di
data.CNR.it