http://www.cnr.it/ontology/cnr/individuo/prodotto/ID195019
Development of a gold-nanostructured surface for amperometric genosensors (Articolo in rivista)
- Type
- Label
- Development of a gold-nanostructured surface for amperometric genosensors (Articolo in rivista) (literal)
- Anno
- 2012-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1007/s11051-012-1148-2 (literal)
- Alternative label
Zanardi, C; Baldoli, C; Licandro, E; Terzi, F; Seeber, R. (2012)
Development of a gold-nanostructured surface for amperometric genosensors
in Journal of nanoparticle research; SPRINGER, DORDRECHT (Paesi Bassi)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Zanardi, C; Baldoli, C; Licandro, E; Terzi, F; Seeber, R. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Univ Modena & Reggio Emilia, Dipartimento Chim, Modena, Italy
CNR, Ist Sci & Tecnol Mol, I-20133 Milan, Italy
Univ Milan, Dipartimento Chim Organ & Ind, Milan, Italy (literal)
- Titolo
- Development of a gold-nanostructured surface for amperometric genosensors (literal)
- Abstract
- A gold-nanostructured surface has been obtained by stable deposition of chemically synthesized gold nanoparticles (2.1-5.5 nm size range) on a gold substrate through a dithiol linker. The method proposed for the obtainment of the nanostructure is suitable for the further stable anchoring of a peptide nucleic acid oligomer through four amine groups of lysine terminal residues, leading to fairly reproducible systems. The geometric area of the nanostructured surface is compared with those of a smooth and of an electrochemically generated nanostructured surface by depositing a probe bearing an electrochemically active ferrocene residue. Despite the area of the two nanostructures being quite similar, the response toward a 2 nM target oligonucleotide sequence is particularly high when using the surface built up by nanoparticle deposition. This aspect indicates that morphologic details of the nanostructure play a key role in conditioning the performances of the genosensors. (literal)
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- Autore CNR
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