Multiple functionalization of fluorescent nanoparticles for specific biolabeling and drug delivery of dopamine. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Multiple functionalization of fluorescent nanoparticles for specific biolabeling and drug delivery of dopamine. (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1039/c1nr10797f (literal)

Alternative label

• Malvindi MA., Di Corato R., Curcio A., Melisi D., Rimoli MG., Tortiglione C., Tino A., George C., Brunetti V., Cingolani R., Pellegrino t., Ragusa A. (2011)
  Multiple functionalization of fluorescent nanoparticles for specific biolabeling and drug delivery of dopamine.
  in Nanoscale (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Malvindi MA., Di Corato R., Curcio A., Melisi D., Rimoli MG., Tortiglione C., Tino A., George C., Brunetti V., Cingolani R., Pellegrino t., Ragusa A. (literal)

Pagina inizio

• 5110 (literal)

Pagina fine

• 5119 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 3 (literal)

Rivista

• Nanoscale (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• Nanoscale 3, 5010-5019 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 12 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Natl Nanotechnol Lab CNR NANO, I-73100 Lecce, Italy. IIT, CBN, I-73010 Lecce, Italy. Italian Inst Technol, I-16163 Genoa, Italy. Univ Naples Federico 2, Sch Pharm, Dept Pharmaceut & Toxicol Chem, I-80131 Naples, Italy. CNR, Ist Cibernet E Caianiello ICIB, I-80078 Naples, Italy. (literal)

Titolo

• Multiple functionalization of fluorescent nanoparticles for specific biolabeling and drug delivery of dopamine. (literal)

Abstract

• The development of fluorescent biolabels for specific targeting and controlled drug release is of paramount importance in biological applications due to their potential in the generation of novel tools for simultaneous diagnosis and treatment of diseases. Dopamine is a neurotransmitter involved in several neurological diseases, such as Parkinson's disease and attention deficit hyperactivity disorder (ADHD), and the controlled delivery of its agonists already proved to have beneficial effects both in vitro and in vivo. Here, we report the synthesis and multiple functionalization of highly fluorescent CdSe/CdS quantum rods for specific biolabeling and controlled drug release. After being transferred into aqueous media, the nanocrystals were made highly biocompatible through PEG conjugation and covered by a carbohydrate shell, which allowed specific GLUT-1 recognition. Controlled attachment of dopamine through an ester bond also allowed hydrolysis by esterases, yielding a smart nanotool for specific biolabeling and controlled drug release. (literal)

Prodotto di

• Nanotecnologie per terapia genica, bioimaging e delivery di farmaci (MD.P01.025.005) (Modulo)
• Sistema Nervoso, Biomolecole e Nanobioscienze (MD.P01.025.007) (Modulo)
• Istituto di cibernetica \"Edoardo Caianiello\" (ISASI) (Istituto)

Autore CNR

• ANGELA TINO (Persona)
• TERESA PELLEGRINO (Persona)
• CLAUDIA TORTIGLIONE (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "Multiple functionalization of fluorescent nanoparticles for specific biolabeling and drug delivery of dopamine." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• CLAUDIA TORTIGLIONE (Unità di personale interno)
• ANGELA TINO (Persona)
• TERESA PELLEGRINO (Persona)

Prodotto

• Istituto di cibernetica \"Edoardo Caianiello\" (ISASI) (Istituto)
• Sistema Nervoso, Biomolecole e Nanobioscienze (MD.P01.025.007) (Modulo)
• Nanotecnologie per terapia genica, bioimaging e delivery di farmaci (MD.P01.025.005) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Nanoscale (Rivista)

Insieme di parole chiave di

• Parole chiave di "Multiple functionalization of fluorescent nanoparticles for specific biolabeling and drug delivery of dopamine." (Insieme di parole chiave)