Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.3233/JAD-2012-121309 (literal)

Alternative label

• Rocco Maria Luisa1; Pristerà Andrea1; Pistillo Luana1;Aloe Luigi1;Canu Nadia1,2; Manni Luigi3 (2013)
  Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture
  in Journal of Alzheimer's disease
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Rocco Maria Luisa1; Pristerà Andrea1; Pistillo Luana1;Aloe Luigi1;Canu Nadia1,2; Manni Luigi3 (literal)

Pagina inizio

• 767 (literal)

Pagina fine

• 773 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• 2012 Sep 21. [Epub ahead of print] (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 33 (literal)

Rivista

• Journal of Alzheimer's disease (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1 Cellular Biology and Neurobiology Institute, National Research Council (CNR), Rome, Italy. 2 Department of Systems Medicine, University of Rome \"Tor Vergata\", Rome, Italy. 3I nstitute of Translational Pharmacology, National Research Council (CNR), Rome, Italy. (literal)

Titolo

• Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture (literal)

Abstract

• Diabetes often correlates with tau phosphorylation and the development of Alzheimer's disease. Both are associated with brain cholinergic dysfunction that could benefit from nerve growth factor (NGF)-based therapies. Electroacupuncture (EA) improves brain NGF availability and action. Here we assessed the variations of NGF and tau phosphorylation in the cortex and hippocampus, as well as the expression of choline acetyltransferase in the basal forebrain following diabetes induction and EA in adult rats. We found that EA counteracts diabetes-associated tau hyperphosphorylation and decreases in NGF and choline acetyltransferase, suggesting a possible beneficial effect of EA on brain cholinergic system in diabetes. (literal)

Prodotto di

• ex ME.P02.010.001 / Patologie del S.N. e Fattori di Crescita (ME.P02.010.004) (Modulo)

Autore CNR

• Maria Luisa Rocco (Persona)
• LUIGI ALOE (Unità di personale esterno)
• nadia canu (Persona)

Insieme di parole chiave

• Parole chiave di "Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture" (Insieme di parole chiave)

Incoming links:

Prodotto

• ex ME.P02.010.001 / Patologie del S.N. e Fattori di Crescita (ME.P02.010.004) (Modulo)

Autore CNR di

• Maria Luisa Rocco (Persona)
• nadia canu (Persona)
• LUIGI ALOE (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of Alzheimer's disease (Rivista)

Insieme di parole chiave di

• Parole chiave di "Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture" (Insieme di parole chiave)