Novel stereoselective synthesis of 1,2,3-trisubstituted azetidines (Articolo in rivista)

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  • Novel stereoselective synthesis of 1,2,3-trisubstituted azetidines (Articolo in rivista) (literal)
Anno
  • 2012-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.tetasy.2012.10.014 (literal)
Alternative label
  • Faigl, Ferenc; Kovács, Ervin; Turczel, Gábor; Szöllosy, Áron; Mordini, Alessandro; Balázs, László; Holczbauer, Tamás; Czugler, Mátyás (2012)
    Novel stereoselective synthesis of 1,2,3-trisubstituted azetidines
    in Tetrahedron: asymmetry (Print); Elsevier, Oxford (Regno Unito)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Faigl, Ferenc; Kovács, Ervin; Turczel, Gábor; Szöllosy, Áron; Mordini, Alessandro; Balázs, László; Holczbauer, Tamás; Czugler, Mátyás (literal)
Pagina inizio
  • 1607 (literal)
Pagina fine
  • 1614 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://www.sciencedirect.com/science/article/pii/S0957416612005253# (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 23 (literal)
Rivista
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  • 8 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • MTA-BME Organic Chemical Technology Research Group, Budapest University of Technology and Economics, Budafoki út 8, H-1111 Budapest, Hungary Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Gellért tér 4, H-1111 Budapest, Hungary CNR Istituto di Chimica dei Composti Organometallici, Dipt.Chim., Università di Firenze. Via della Lastruccia 13, 50019 Sesto Fiorentino, Firenze, Italy R&D of Chinoin Ltd, External Pharmaceutical Department, Budapest University of Technology and Economics, Tó utca 1-5, H-1045 Budapest, Hungary Institute of Structural Chemistry, Hungarian Academy of Sciences, Pusztaszeri út 59-67, H-1025 Budapest, Hungary (literal)
Titolo
  • Novel stereoselective synthesis of 1,2,3-trisubstituted azetidines (literal)
Abstract
  • A novel, superbase induced diastereoselective transformation of benzylamino groups containing oxiranes has provided a series of trans-1,2,3-trisubstituted azetidines in good yields. The reaction of the corresponding optically active cis-2,3-disubstituted oxirane yielded the azetidine derivative as a single enantiomer. The structures of the new azetidines were confirmed by NMR spectroscopic methods and, in one case, by single crystal diffraction measurements. (literal)
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