Bioconjugation of rod-shaped nanocrystals for efficient targeted cell labelling (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Bioconjugation of rod-shaped nanocrystals for efficient targeted cell labelling (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1021/la901831y (literal)

Alternative label

• Quarta A; Ragusa A; Deka S; Tortiglione C; Tino A; Cingolani R; Pellegrino T; (2009)
  Bioconjugation of rod-shaped nanocrystals for efficient targeted cell labelling
  in Langmuir
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Quarta A; Ragusa A; Deka S; Tortiglione C; Tino A; Cingolani R; Pellegrino T; (literal)

Pagina inizio

• 12614 (literal)

Pagina fine

• 12622 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 25 (literal)

Rivista

• Langmuir (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 9 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 21 (literal)

Note

• Scopu (literal)
• ISI Web of Science (WOS) (literal)
• PubMe (literal)
• Google Scholar (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR, Ist Cibernet E Caianiello, I-80078 Pozzuoli, Italy; CNR INFM, Natl Nanotechnol Lab, I-73100 Lecce, Italy; IIT Res Unit, I-73100 Lecce, Italy; Italian Inst Technol, I-16163 Genoa, Italy; (literal)

Titolo

• Bioconjugation of rod-shaped nanocrystals for efficient targeted cell labelling (literal)

Abstract

• In the present work, we report a three-step approach for the functionalization of CdSe/CdS core/shell and CdSe/CdS/ZnS double-shell quantum rods (QRs) with either biotin or folic acid. We carried out an in vitro study on cultured cells and fixed tissue sections in which the biofunctionalized QRs were compared with the more traditional CdSe/ZnS quantum dots (QDs), which were also functionalized with either biotin or folic acid. The QR and the QD samples exhibited the same specificity toward the targeting cells. In addition, due to the enhanced photoluminescence of the QRs with respect to QDs, a lower amount of rods was required to image cells. In immuno-localization experiments on rat brain tissue sections, biotin-functionalized QRs have shown the typical protein localization patterns expected both for neuronal enolase NSE and actin, confirming the specificity of the interaction of QRs with avidin, and the feasibility of these materials as fluorescent probes in tissue staining, In this specific targeting study, we could assess via the MTT test, a cell viability assay, the lower toxicity Of the CdSe/CdS/ZnS QRs with respect to CdSe/CdS QRs. (literal)

Prodotto di

• Istituto di cibernetica \"Edoardo Caianiello\" (ISASI) (Istituto)
• Meccanismi di trasmissione e trasduzione di segnali cellulari (MD.P01.006.001) (Modulo)

Autore CNR

• CLAUDIA TORTIGLIONE (Unità di personale interno)
• TERESA PELLEGRINO (Unità di personale interno)
• ANGELA TINO (Persona)

Insieme di parole chiave

• Parole chiave di "Bioconjugation of rod-shaped nanocrystals for efficient targeted cell labelling" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• CLAUDIA TORTIGLIONE (Unità di personale interno)
• ANGELA TINO (Persona)
• TERESA PELLEGRINO (Unità di personale interno)

Prodotto

• Istituto di cibernetica \"Edoardo Caianiello\" (ISASI) (Istituto)
• Meccanismi di trasmissione e trasduzione di segnali cellulari (MD.P01.006.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Langmuir (Rivista)

Insieme di parole chiave di

• Parole chiave di "Bioconjugation of rod-shaped nanocrystals for efficient targeted cell labelling" (Insieme di parole chiave)