Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture. (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.3233/JAD-2012-121309 (literal)

Alternative label

• Rocco ML; Pristerà A; Pistillo L; Aloe L; Canu N; Manni L (2013)
  Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture.
  in Journal of Alzheimer's disease
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Rocco ML; Pristerà A; Pistillo L; Aloe L; Canu N; Manni L (literal)

Pagina inizio

• 767 (literal)

Pagina fine

• 773 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://iospress.metapress.com/content/u212k3p481366542/?genre=article&id=doi%3a10.3233%2fJAD-2012-121309 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 33 (literal)

Rivista

• Journal of Alzheimer's disease (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Cellular Biology and Neurobiology Institute, National Research Council (CNR), Rome, Italy. Institute of Translational Pharmacology, National Research Council (CNR), Rome, Italy (literal)

Titolo

• Brain Cholinergic Markers and Tau Phosphorylation are Altered in Experimental Type 1 Diabetes: Normalization by Electroacupuncture. (literal)

Abstract

• Diabetes often correlates with tau phosphorylation and the development of Alzheimer's disease. Both are associated with brain cholinergic dysfunction that could benefit from nerve growth factor (NGF)-based therapies. Electroacupuncture (EA) improves brain NGF availability and action. Here we assessed the variations of NGF and tau phosphorylation in the cortex and hippocampus, as well as the expression of choline acetyltransferase in the basal forebrain following diabetes induction and EA in adult rats. We found that EA counteracts diabetes-associated tau hyperphosphorylation and decreases in NGF and choline acetyltransferase, suggesting a possible beneficial effect of EA on brain cholinergic system in diabetes. (literal)

Prodotto di

• Traslazionalità di approcci terapeutici integrativi (ME.P04.009.004) (Modulo)

Autore CNR

• LUIGI MANNI (Unità di personale interno)
• Maria Luisa Rocco (Persona)
• LUIGI ALOE (Unità di personale esterno)

Incoming links:

Autore CNR di

• LUIGI MANNI (Unità di personale interno)
• Maria Luisa Rocco (Persona)
• LUIGI ALOE (Unità di personale esterno)

Prodotto

• Traslazionalità di approcci terapeutici integrativi (ME.P04.009.004) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of Alzheimer's disease (Rivista)