Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Alternative label

• Giovanni Delogu a; Michela Sali a; Stefano Rocca b; Gianluca Quintiliani c; Marilina B. Santucci c; Emanuela Greco c; Andrea Cabibbo c; Francesca Mariani d; Vittorio Colizzi c; Giovanni Fadda a; Maurizio Fraziano c (2011)
  Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection
  in Cellular immunology (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Giovanni Delogu a; Michela Sali a; Stefano Rocca b; Gianluca Quintiliani c; Marilina B. Santucci c; Emanuela Greco c; Andrea Cabibbo c; Francesca Mariani d; Vittorio Colizzi c; Giovanni Fadda a; Maurizio Fraziano c (literal)

Pagina inizio

• 1 (literal)

Pagina fine

• 4 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://dx.doi.org/10.1016/j.cellimm.2011.05.014 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 271 (literal)

Rivista

• Cellular immunology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 4 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• a Institute of Microbiology, Catholic University of the Sacred Heart, 00168 Rome, Italy. b Institute of General Pathology, Pathological Anatomy and Veterinary Obstetrics-Surgery Clinics, University of Sassari, 07100 Sassari, Italy. c Department of Biology, University of Rome \"Tor Vergata\", 00133 Rome, Italy. d Institute of Neurobiology and Molecular Medicine, National Research Council, 00133 Rome, Italy. (literal)

Titolo

• Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection (literal)

Abstract

• Lysophospholipids may play an important protective role during primary infection of Mycobacterium tuberculosis (MTB) by enhancing innate antimycobacterial immune response of both macrophages and alveolar epithelial cells. Here, we show that treatment with lysophosphatidic acid (LPA) of mice aerogenically infected with MTB immediately after infection results in a significant early reduction of pulmonary CFUs and of histopathological damage in comparison with control mice. In contrast, treatment of acute disease does not result in any improvement of both microbiological and histopathological parameters. Altogether, these results show that LPA treatment can exert protective effect if administrated during primary infection, only (literal)

Prodotto di

• ex ME.P03.007.001 / Meccanismi regolativi del Differenziamento e Oncogenesi (ME.P03.007.002) (Modulo)

Autore CNR

• FRANCESCA MARIANI (Persona)

Insieme di parole chiave

• Parole chiave di "Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• FRANCESCA MARIANI (Persona)

Prodotto

• ex ME.P03.007.001 / Meccanismi regolativi del Differenziamento e Oncogenesi (ME.P03.007.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Cellular immunology (Rivista)

Insieme di parole chiave di

• Parole chiave di "Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection" (Insieme di parole chiave)