The mammalian gene function resource: the international knockout mouse consortium (Articolo in rivista)

Type
Label
  • The mammalian gene function resource: the international knockout mouse consortium (Articolo in rivista) (literal)
Anno
  • 2012-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1007/s00335-012-9422-2 (literal)
Alternative label
  • Allan Bradley 1; Konstantinos Anastassiadis 2; Abdelkader Ayadi 3; James F. Battey 4; Cindy Bell 5; Marie-Christine Birling 3; Joanna Bottomley 1; Steve D. Brown 6; Antje Burger 7; Carol J. Bult 8; Wendy Bushell 1; Francis S. Collins 9; Christian Desaintes 10; Brendan Doe 11; Aris Economides 12; Janan T. Eppig 8; Richard H. Finnell 13,14; Colin Fletcher 15; Martin Fray 6; David Frendewey 12; Roland H. Friedel 7,35; Frank G. Grosveld 16; Jens Hansen 7; Yann Hérault 3; Geoffrey Hicks 17; Andreas Horlein 7; Richard Houghton 1; Martin Hrabé de Angelis 18; Danny Huylebroeck 19; Vivek Iyer 1; Pieter J. de Jong 20; James A. Kadin 8; Cornelia Kaloff 7; Karen Kennedy 1; Manousos Koutsourakis 1; K. C. Kent Lloyd 21; Susan Marschall 18; Jeremy Mason,8 Colin McKerlie,22 Michael P. McLeod,13 Harald von Melchner,23 Mark Moore,15 Alejandro O. Mujica 1,12; Andras Nagy 25; Mikhail Nefedov 20; Lauryl M. Nutter 22; Guillaume Pavlovic 3; Jane L. Peterson 15; Jonathan Pollock 26; Ramiro Ramirez-Solis 1; Derrick E. Rancourt 27; Marcello Raspa 11; Jacques E. Remacle 10; Martin Ringwald 8; Barry Rosen 1; Nadia Rosenthal 28; Janet Rossant 22; Patricia Ruiz Noppinger 29; Ed Ryder 1; Joel Zupicich Schick 7; Frank Schnutgen 23; Paul Schofield 30; Claudia Seisenberger 7; Mohammed Selloum 3; Elizabeth M. Simpson 31; William C. Skarnes 1; Damian Smedley 1,32; William L. Stanford 33; A. Francis Stewart 2; Kevin Stone 8; Kate Swan 5; Hamsa Tadepally 8; Lydia Teboul 6; Glauco P. Tocchini-Valentini; 11 David Valenzuela 12; Anthony P. West 1; Ken-ichi Yamamura 34; Yuko Yoshinaga 20; Wolfgang Wurst 7,36,37 (2012)
    The mammalian gene function resource: the international knockout mouse consortium
    in Mammalian genome (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Allan Bradley 1; Konstantinos Anastassiadis 2; Abdelkader Ayadi 3; James F. Battey 4; Cindy Bell 5; Marie-Christine Birling 3; Joanna Bottomley 1; Steve D. Brown 6; Antje Burger 7; Carol J. Bult 8; Wendy Bushell 1; Francis S. Collins 9; Christian Desaintes 10; Brendan Doe 11; Aris Economides 12; Janan T. Eppig 8; Richard H. Finnell 13,14; Colin Fletcher 15; Martin Fray 6; David Frendewey 12; Roland H. Friedel 7,35; Frank G. Grosveld 16; Jens Hansen 7; Yann Hérault 3; Geoffrey Hicks 17; Andreas Horlein 7; Richard Houghton 1; Martin Hrabé de Angelis 18; Danny Huylebroeck 19; Vivek Iyer 1; Pieter J. de Jong 20; James A. Kadin 8; Cornelia Kaloff 7; Karen Kennedy 1; Manousos Koutsourakis 1; K. C. Kent Lloyd 21; Susan Marschall 18; Jeremy Mason,8 Colin McKerlie,22 Michael P. McLeod,13 Harald von Melchner,23 Mark Moore,15 Alejandro O. Mujica 1,12; Andras Nagy 25; Mikhail Nefedov 20; Lauryl M. Nutter 22; Guillaume Pavlovic 3; Jane L. Peterson 15; Jonathan Pollock 26; Ramiro Ramirez-Solis 1; Derrick E. Rancourt 27; Marcello Raspa 11; Jacques E. Remacle 10; Martin Ringwald 8; Barry Rosen 1; Nadia Rosenthal 28; Janet Rossant 22; Patricia Ruiz Noppinger 29; Ed Ryder 1; Joel Zupicich Schick 7; Frank Schnutgen 23; Paul Schofield 30; Claudia Seisenberger 7; Mohammed Selloum 3; Elizabeth M. Simpson 31; William C. Skarnes 1; Damian Smedley 1,32; William L. Stanford 33; A. Francis Stewart 2; Kevin Stone 8; Kate Swan 5; Hamsa Tadepally 8; Lydia Teboul 6; Glauco P. Tocchini-Valentini; 11 David Valenzuela 12; Anthony P. West 1; Ken-ichi Yamamura 34; Yuko Yoshinaga 20; Wolfgang Wurst 7,36,37 (literal)
Pagina inizio
  • 580 (literal)
Pagina fine
  • 586 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 23 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 6 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 9-10 (literal)
Note
  • PubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1 The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH UK. 2 Biotechnology Center (BIOTEC) of the Technische Universität Dresden, 01307 Dresden, Germany. 3 Institut Clinique de la Souris and Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch Cedex, France. 4 National Institute on Deafness and Other Communication Disorders (NIH), Bethesda, MD 20892 USA 5 Genome Canada, Ottawa, ON K2P 1P1 Canada. 6 Mammalian Genetics Unit, MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD UK. 7 Institute of Developmental Genetics, Helmholtz Zentrum München, Technische Universität München, 85764 Neuherberg, Germany. 8 The Jackson Laboratory, Bar Harbor, ME 04609 USA. 9 National Institutes of Health, Bethesda, MD 20892 USA. 10 Infectious Diseases and Public Health, European Commission, DG Research & Innovation, 1049 Brussels, Belgium. 11 Istituto di Biologia Cellulare, Consiglio Nazionale delle Ricerche (CNR), Monterotondo-Scalo, 00015 Rome, Italy. 12 Velocigene Division, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591 USA. 13 The Texas A&M Institute for Genomic Medicine, College Station, TX 77843-4485 USA. 14 University of Texas at Austin, Austin, TX 78712 USA. 15 National Institutes of Health, Bethesda, MD 20205 USA. 16 Department of Cell Biology, Center of Biomedical Genetics, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands. 17 Manitoba Institute of Cell Biology, University of Manitoba, Winnipeg, MB R3E OV9 Canada. 18 Institute of Experimental Genetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany. 19 Department of Development and Regeneration, Faculty of Medicine, University of Leuven (KU Leuven), 3000 Leuven, Belgium. 20 Children's Hospital Oakland Research Institute (CHORI), Oakland, CA 94609 USA. 21 Mouse Biology Program, School of Veterinary Medicine, University of California, Davis, CA 95616 USA. 22 Research Institute, The Hospital for Sick Children, SickKids Foundation, Toronto, ON M5G2L3 Canada. 23 Department of Molecular Haematology, University of Frankfurt Medical School, 60590 Frankfurt am Main, Germany. 25 Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, ON M5G 1X5 Canada. 26 Division of Basic Neuroscience and Research, National Institute of Drug Abuse (NIDA), Bethesda, MD 20892-0001 USA. 27 Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB T2N 1N4 Canada. 28 European Molecular Biology Laboratory (EMBL), Monterotondo, 00015 Rome, Italy. 29 Centre for Cardiovascular Research, Department of Vertebrate Genomics, Charité, 10115 Berlin, Germany. 30 Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG UK. 31 Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics at the Child & Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4 Canada. 32 European Bioinformatics Institute (EBI), Hinxton, Cambridge, CB10 1ST UK. 33 The Ottawa Hospital Research Institute, Ottawa, ON K1N 6N5 Canada. 34 Division of Developmental Genetics, Center for Animal Resources and Development, Institute of Resource Development and Analysis, Kumamoto University, Kumamoto, 860-0811 Japan. 35 Icahn Medical Institute, The Mount Sinai Hospital, New York, NY 10029 USA. 36 Max-Planck-Institute of Psychiatry, 80804 Munich, Germany. 37 Deutsches Zentrum fuer Neurodegenerative Erkrankungen e.V. (DZNE) Site Munich, 80336 Munich, Germany. (literal)
Titolo
  • The mammalian gene function resource: the international knockout mouse consortium (literal)
Abstract
  • In 2007, the International Knockout Mouse Consortium (IKMC) made the ambitious promise to generate mutations in virtually every protein-coding gene of the mouse genome in a concerted worldwide action. Now, 5 years later, the IKMC members have developed high-throughput gene trapping and, in particular, gene-targeting pipelines and generated more than 17,400 mutant murine embryonic stem (ES) cell clones and more than 1,700 mutant mouse strains, most of them conditional. A common IKMC web portal ( www.knockoutmouse.org ) has been established, allowing easy access to this unparalleled biological resource. The IKMC materials considerably enhance functional gene annotation of the mammalian genome and will have a major impact on future biomedical research. (literal)
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