Early Diagnosis of Congenital Trypanosoma cruzi Infection Using PCR, Hemoculture and Capillary Concentration, as compared to Delayed Serology (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Early Diagnosis of Congenital Trypanosoma cruzi Infection Using PCR, Hemoculture and Capillary Concentration, as compared to Delayed Serology (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Alternative label

• MORA M.C.; SANCHEZ NEGRETTE O.; MARCO D.; CIACCIO M.; BARRIO A.; SEGURA M.A.; BASOMBRIO M.A. (2006)
  Early Diagnosis of Congenital Trypanosoma cruzi Infection Using PCR, Hemoculture and Capillary Concentration, as compared to Delayed Serology
  in The Journal of parasitology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• MORA M.C.; SANCHEZ NEGRETTE O.; MARCO D.; CIACCIO M.; BARRIO A.; SEGURA M.A.; BASOMBRIO M.A. (literal)

Pagina inizio

• 1468 (literal)

Pagina fine

• 1473 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 91 (literal)

Rivista

• ?The ?Journal of parasitology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 5 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Instituto de Patología Experimental, Facultad de Ciencias de la Salud, Universidad Nacional de Salta, Argentina Istituto di Biomedicina e Immunologia Molecolare, CNR, via Ugo La Malfa 153, 90146 palermo, italy (literal)

Titolo

• Early Diagnosis of Congenital Trypanosoma cruzi Infection Using PCR, Hemoculture and Capillary Concentration, as compared to Delayed Serology (literal)

Abstract

• Congenital Trypanosoma cruzi infection is a highly pathogenic and underreported condition. Early recognition is essential for effective treatment. Umbilical chord blood from newborns (n = 302) to infected mothers was analyzed with microhematocrit, hemoculture, and PCR methods. Each subject was then followed serologically. In calibrated suspensions of T. cruzi in blood, the sensitivity of PCR was 27-fold higher than hemoculture. However, this advantage was not reflected during routine testing of samples from maternities, partly because of the uneven distribution of few parasites in small samples. Levels of detection of congenital infection were 2.9% (8/272) for microhematocrit, 6.3% (18/287) for hemoculture, 6.4% (15/235) for PCR, and 8.9% (27/302) for cumulated results. Evaluation against the standard of delayed serology indicates that the regular application of PCR, hemoculture, and microhematocrit to blood samples allows the rapid detection of about 90% of the congenitally infected newborns, in samples that can be obtained before the mother and child leave the maternity ward. (literal)

Prodotto di

• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)

Autore CNR

• MIRELLA CIACCIO (Unità di personale interno)

Incoming links:

Prodotto

• Istituto di biomedicina e di immunologia molecolare \"Alberto Monroy\" (IBIM) (Istituto)

Autore CNR di

• MIRELLA CIACCIO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• ?The ?Journal of parasitology (Rivista)