Differential expression pattern of XqPAR-linked genes SYBL1 and IL9R correlates with the structure and evolution of the region (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Differential expression pattern of XqPAR-linked genes SYBL1 and IL9R correlates with the structure and evolution of the region (Articolo in rivista) (literal)

Anno

• 1997-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1093/hmg/6.11.1917 (literal)

Alternative label

• DEsposito, M; Matarazzo, MR; Ciccodicola, A; Strazzullo, M; Matzarella, R; Quaderi, NA; Fujiwara, H; Ko, MSH; Rowe, LB; Ricco, A; Archidiacono, N; Rocchi, M; Schlessinger, D; DUrso, M (1997)
  Differential expression pattern of XqPAR-linked genes SYBL1 and IL9R correlates with the structure and evolution of the region
  in Human molecular genetics (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• DEsposito, M; Matarazzo, MR; Ciccodicola, A; Strazzullo, M; Matzarella, R; Quaderi, NA; Fujiwara, H; Ko, MSH; Rowe, LB; Ricco, A; Archidiacono, N; Rocchi, M; Schlessinger, D; DUrso, M (literal)

Pagina inizio

• 1917 (literal)

Pagina fine

• 1923 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 6 (literal)

Rivista

• Human molecular genetics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 11 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR,INT INST GENET & BIOPHYS,I-80125 NAPLES,ITALY WASHINGTON UNIV,SCH MED,DEPT MOL MICROBIOL,ST LOUIS,MO 63110 DIBIT,TELETHON INST GENET & MED,I-20132 MILAN,ITALY WAYNE STATE UNIV,SCH MED,CTR MOL MED & GENET,DETROIT,MI 48202 JACKSON LAB,BAR HARBOR,ME 04609 UNIV BARI,IST GENET,I-70126 BARI,ITALY (literal)

Titolo

• Differential expression pattern of XqPAR-linked genes SYBL1 and IL9R correlates with the structure and evolution of the region (literal)

Abstract

• The recently discovered second pseudoautosomal region (XqPAR) contains at least two genes, IL9R and SYBL1. Recent findings show that, like XpPAR genes, IL9R escapes X inactivation and its Y allele is also expressed, but SYBL1 seems to act like an X-linked gene, expressed from the active X chromosome but not from the inactive X or Y. Here we show that differences are also seen in the evolution of the sex chromosome locations of IL9R and SYBL1, IL9R is known to be autosomal in mice, and is X-linked only in primates. SYBL1, however, has been found to be on the X chromosome in all mammals tested, from marsupials to humans, Both genes were duplicated on the Y homologue of the terminal portion of the X chromosome during the evolution of Homo sapiens from other higher primates. The inactivation pattern of SYBL1 may be correlated with its longer history of X linkage, and at a more centromeric chromosomal position during evolution; the more recent X linkage and more telomeric position of the IL9R gene may explain its autosomal, 'uninactivated' transcriptional status. (literal)

Prodotto di

• Istituto di genetica e biofisica \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Autore CNR

• MARIA STRAZZULLO (Persona)
• MAURIZIO D'ESPOSITO (Persona)
• MICHELE D'URSO (Unità di personale interno)
• ALFREDO CICCODICOLA (Persona)
• MARIA ROSARIA MATARAZZO (Unità di personale interno)

Incoming links:

Autore CNR di

• MICHELE D'URSO (Unità di personale interno)
• MAURIZIO D'ESPOSITO (Persona)
• MARIA STRAZZULLO (Persona)
• ALFREDO CICCODICOLA (Persona)
• MARIA ROSARIA MATARAZZO (Unità di personale interno)

Prodotto

• Istituto di genetica e biofisica \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Human molecular genetics (Rivista)