Nerve growth factor and tissue repair remodeling: trkANGFR and p75NTR, two receptors one fate (Articolo in rivista)

Type
Label
  • Nerve growth factor and tissue repair remodeling: trkANGFR and p75NTR, two receptors one fate (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.cytogfr.2007.04.004 (literal)
Alternative label
  • Alessandra Micera (a,b); Alessandro Lambiase (c); Barbara Stampachiacchiere (b,c); Stefano Bonini (c); Sergio Bonini (d); Francesca Levi-Schaffer (a,e). (2007)
    Nerve growth factor and tissue repair remodeling: trkANGFR and p75NTR, two receptors one fate
    in Cytokine & growth factor reviews
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Alessandra Micera (a,b); Alessandro Lambiase (c); Barbara Stampachiacchiere (b,c); Stefano Bonini (c); Sergio Bonini (d); Francesca Levi-Schaffer (a,e). (literal)
Pagina inizio
  • 245 (literal)
Pagina fine
  • 256 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 18 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 12 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 3-4 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • a) Department of Pharmacology, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel; b) IRCCS-G.B. Bietti Eye Foundation, Rome, Italy; c) CIR, Laboratory of Ophthalmology, University Campus Bio-Medico, Rome, Italy; d) Second University of Naples and Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy; e) David R. Bloom Center of the School of Pharmacy, The Hebrew University of Jerusalem, Israel (literal)
Titolo
  • Nerve growth factor and tissue repair remodeling: trkANGFR and p75NTR, two receptors one fate (literal)
Abstract
  • This review deals with the role of nerve growth factor (NGF) in healing process as a result of injury. The role of both trkA(NGFR) and p75(NTR) specific NGF receptors and their contribution in the complex network of tissue repair process, is discussed and highlighted in view of recent findings. In fact, NGF represents a significant advance in the treatment of etiologically different ulcers (corneal ulcers, pressure ulcers, post-viral infections, chemical burns) and might shorten the recovery process. For these diseases, no specific treatment is actually available. It is reasonable that apart from NGF and/or neurotrophins a different time-course of trkA(NGRF)/p75(NTR) expression, might regulate the final process. In summary, these novel findings on the potential pro-healing capacity of NGF might open new possibilities for this growth factor in modulating the healing processes in several pathological conditions. (literal)
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