http://www.cnr.it/ontology/cnr/individuo/prodotto/ID18518
Preliminary chemico-biological studies on Ru(III) compounds with S-methyl pyrrolidine/dimethyl dithiocarbamate (Articolo in rivista)
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- Label
- Preliminary chemico-biological studies on Ru(III) compounds with S-methyl pyrrolidine/dimethyl dithiocarbamate (Articolo in rivista) (literal)
- Anno
- 2009-01-01T00:00:00+01:00 (literal)
- Alternative label
Giovagnini L. 1, Mancinetti E. 1, Ronconi L. 1, Sitran S. 2, Marchio L. 3,5, Castagliuolo I. 4, Brun P. 4, Trevisan A. ,Fregona D. 1 (2009)
Preliminary chemico-biological studies on Ru(III) compounds with S-methyl pyrrolidine/dimethyl dithiocarbamate
in Journal of inorganic biochemistry
(literal)
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- Giovagnini L. 1, Mancinetti E. 1, Ronconi L. 1, Sitran S. 2, Marchio L. 3,5, Castagliuolo I. 4, Brun P. 4, Trevisan A. ,Fregona D. 1 (literal)
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- 1. Univ Padua, Dept Chem Sci, I-35131 Padua, Italy
2. CNR, Res Area, Inst Inorgan & Surfaces Chem, I-35127 Padua, Italy
3. Univ Parma, Dept Gen & Inorgan Chem, I-43100 Parma, Italy
4. Univ Padua, Dept Histol Microbiol & Med Biotechnol, Sect Microbiol & Virol, I-35131 Padua, Italy
5. Univ Padua, Dept Environm Med & Publ Hlth, I-35128 Padua, Italy (literal)
- Titolo
- Preliminary chemico-biological studies on Ru(III) compounds with S-methyl pyrrolidine/dimethyl dithiocarbamate (literal)
- Abstract
- [RuCl3 center dot nH(2)O] and Na(trans-[RuCl4(DMSO)(2)])D were reacted with 1-pyrrolidinedithiocarbamate (PDT). its S-rnethyl ester (PDTM), and N,N-dimethylcarbamodithioic acid methyl ester (DMDTM) in water or methanol in order to obtain the corresponding Ru(III) derivatives. Once isolated and purified, the complexes were characterized by means of elemental analysis, conductivity measurements, FT-IR and H-1 NMR spectroscopy, ion electrospray mass spectrometry (ESI-MS), and thermal analyses. The crystal structure of mer-[Ru(DMDTM)(DMSO)Cl-3] has been also determined by X-ray crystallography. In vitro cytotoxic activity of all the synthesized complexes was eventually evaluated on some selected human tumor cell lines. (literal)
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