Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain. (Articolo in rivista) (literal)

Anno

• 2005-01-01T00:00:00+01:00 (literal)

Alternative label

• G. PONTI (a), L. CONTI (b), T. CATAUDELLA (b), C. ZUCCATO (b), L. MAGRASSI (c, d), F. ROSSI (e, f), L. BONFANTI (f), E. CATTANEO (b) (2005)
  Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain.
  in Neuroscience (New York, N.Y. : 1982); ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, AMSTERDAM (Paesi Bassi)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• G. PONTI (a), L. CONTI (b), T. CATAUDELLA (b), C. ZUCCATO (b), L. MAGRASSI (c, d), F. ROSSI (e, f), L. BONFANTI (f), E. CATTANEO (b) (literal)

Pagina inizio

• 105 (literal)

Pagina fine

• 115 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 133 (literal)

Rivista

• Neuroscience (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 11 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)
• Google Scholar (literal)
• PubMe (literal)
• Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• a) Department of Veterinary Morphophysiology, University of Turin, 10095 Grugliasco, Torino, Italy b) Department of Pharmacological Sciences and Center of Excellence on Neurodegenerative Diseases, University of Milano, Milano, Italy c) Istituto di Genetica Molecolare CNR, Pavia d) Neurochirurgia, Dipartimento di Chirurgia, Università di Pavia, IRCCS Policlinico S. Matteo, and I.G.M. CNR, 27100 Pavia, Italy e) Department of Neuroscience, Section of Physiology, University of Turin, 10095 Torino, Italy f) Rita Levi Montalcini Center for Brain Repair, University of Turin, Torino, Italy (literal)

Titolo

• Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain. (literal)

Abstract

• Shc family of adaptor molecules has been demonstrated to play an important role during the transition from proliferating neural stem cells to postmitotic neurons. Previous studies from our group demonstrated a progressive decrease of ShcA levels occurring in coincidence with the end of embryonic neurogenesis and neuronal maturation, being ShcB and ShcC the major Shc molecules expressed in the mature brain. A growing body of evidence indicates that ShcB and ShcC are neuronal specific molecules exerting important roles in neuronal survival and phenotypic stability thus becoming potential attracting target molecules for development of drugs for interfering with brain demises. Here, we examine the expression pattern of ShcB and ShcC in neuronal populations composing the adult central and peripheral nervous system, in order to better elucidate their roles in vivo. We found a heterogeneous and peculiar presence and subcellular localization of ShcB and ShcC in specific neuronal populations, enlightening a potential specific requirement of these two molecules in the survival/maintenance of defined neuronal subtypes. (literal)

Editore

• ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS (Editore)

Prodotto di

• Studio della regolazione post-trascrizionale dell'espressione genica in risposta a stress. Fattori che controllano lo splicing dei mRNA in cellule normali e nei tumori. (SV.P13.001.001) (Modulo)
• Institute of molecular genetics (IGM) (Istituto)

Autore CNR

• Lorenzo Magrassi (Unità di personale esterno)

Insieme di parole chiave

• Parole chiave di "Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain." (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of molecular genetics (IGM) (Istituto)
• Studio della regolazione post-trascrizionale dell'espressione genica in risposta a stress. Fattori che controllano lo splicing dei mRNA in cellule normali e nei tumori. (SV.P13.001.001) (Modulo)

Autore CNR di

• Lorenzo Magrassi (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Neuroscience (Rivista)

Editore di

• ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS (Editore)

Insieme di parole chiave di

• Parole chiave di "Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain." (Insieme di parole chiave)