http://www.cnr.it/ontology/cnr/individuo/prodotto/ID1833
Defects in ordered aggregates of cardiolipin visualized by atomic force microscopy (Articolo in rivista)
- Type
- Label
- Defects in ordered aggregates of cardiolipin visualized by atomic force microscopy (Articolo in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
- Alternative label
Alessandrini, A; Valdre, G; Valdre, U; Muscatello, U (2007)
Defects in ordered aggregates of cardiolipin visualized by atomic force microscopy
in Chemistry and physics of lipids (Print)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Alessandrini, A; Valdre, G; Valdre, U; Muscatello, U (literal)
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- Univ Modena & Reggio Emilia, CNR, INFM, S3 NanoStruct & BioSyst Surfaces, I-41100 Modena, Italy; Univ Modena & Reggio Emilia, Dept Biomed Sci, I-41100 Modena, Italy; Univ Bologna, CNISM, I-40126 Bologna, Italy; Univ Bologna, Dept Earth & Geoenvironm Sci, I-40126 Bologna, Italy; Univ Bologna, Dept Phys, I-40126 Bologna, Italy (literal)
- Titolo
- Defects in ordered aggregates of cardiolipin visualized by atomic force microscopy (literal)
- Abstract
- The formation and the nature of defects in ordered aggregates of cardiolipin (tetra acyl di phosphatidyl glycerol) supported on solid substrates have been investigated by atomic force microscopy (AFM). The experiments were performed on two model systems, i.e. three-dimensional liquid crystals dispersed in water and partially de-hydrated on a hydrophilic surface, and two-dimensional films of molecules self-assembled onto an isotropic hydrophobic surface. Defects were induced both by varying the preparation temperature and by treatment with specific chemicals known to modify the order parameters in natural and artificial membranes, specifically: 2,4-dinitro-phenol (DNP) and pentachloro-phenol (PCP). The effect of lipid oxidation on the nanocrystalline order was also investigated. The images obtained by AFM allow to characterize the type of defects and their local density at nanoscale level. They also provide additional information to differentiate the specific role of acyl chains and polar heads in the process of lipid self-organization. (c) 2007 Elsevier Ireland Ltd. All rights reserved. (literal)
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