Direct Electrospray Ionization Mass Spectrometry Quantitative Analysis of Sebacic and Terephthalic Acids in Biodegradable Polymers (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Direct Electrospray Ionization Mass Spectrometry Quantitative Analysis of Sebacic and Terephthalic Acids in Biodegradable Polymers (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Alternative label

• P.Rizzarelli, D.Zampino, L.Ferreri, G.Impallomeni (2011)
  Direct Electrospray Ionization Mass Spectrometry Quantitative Analysis of Sebacic and Terephthalic Acids in Biodegradable Polymers
  in Analytical chemistry (Wash.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• P.Rizzarelli, D.Zampino, L.Ferreri, G.Impallomeni (literal)

Pagina inizio

• 654 (literal)

Pagina fine

• 660 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 83 (literal)

Rivista

• Analytical chemistry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• ImpactFactor=5,287 (literal)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• Direct Electrospray Ionization Mass Spectrometry Quantitative Analysis of Sebacic and Terephthalic Acids in Biodegradable Polymers (literal)

Abstract

• A direct, rapid, and easy electrospray ionization mass spectrometry (ESI-MS) method to determine concentrations of sebacic acid (SA) and terephthalic acid (TA) residues in biodegradable copolymers was developed. Copolyester samples were synthesized from 1,4-butanediol and sebacic and terephthalic acids by melt polymerization. Extraction of monomers was performed in methanol. Their concentrations were determined by direct infusion ESI-MS, without chromatographic separation, using 1,12-dodecanedioic acid (DDA) as an internal standard. Calibration curves were obtained by plotting the ratio of the areas of the peaks relative to monomers and DDA standard as a function of their concentration ratio. We validated the method by determining the concentration of TA residue using both the ESI-MS protocol and high-performance liquid chromatography (HPLC) analysis with UV detection. The linearity range and the detection limit of this assay were 0.1-5.0 and 0.01 ppm for SA and 0.1-6.0 and 0.03 ppm for TA. This assay represents a useful alternative to conventional methods currently employed for acid quantification, resulting advantageous for its speed and high sensitivity. (literal)

Prodotto di

• Glicomica e Proteomica per la ricerca di biomarcatori per la diagnosi e la terapia di patologie congenite, tumorali e infiammatorie. (PM.P06.013.001) (Modulo)
• 4. Sistemi polimerici innovativi ad elevate prestazioni per applicazioni biomediche ed ambientali (PM.P02.009.001) (Modulo)
• Istituto di chimica e tecnologia dei polimeri (ICTP) (Istituto)

Autore CNR

• DANIELA CLOTILDE ZAMPINO (Persona)
• GIUSEPPE IMPALLOMENI (Persona)
• PAOLA RIZZARELLI (Unità di personale interno)

Incoming links:

Autore CNR di

• DANIELA CLOTILDE ZAMPINO (Persona)
• PAOLA RIZZARELLI (Unità di personale interno)
• GIUSEPPE IMPALLOMENI (Persona)

Prodotto

• Istituto di chimica e tecnologia dei polimeri (ICTP) (Istituto)
• 4. Sistemi polimerici innovativi ad elevate prestazioni per applicazioni biomediche ed ambientali (PM.P02.009.001) (Modulo)
• Glicomica e Proteomica per la ricerca di biomarcatori per la diagnosi e la terapia di patologie congenite, tumorali e infiammatorie. (PM.P06.013.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Analytical chemistry (Rivista)