O-Acetyl location on Cepacian, the principal exopolysaccharide of Burkholderia cepacia complex bacteria (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• O-Acetyl location on Cepacian, the principal exopolysaccharide of Burkholderia cepacia complex bacteria (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Alternative label

• P.Cescutti, G.Impallomeni, D.Garozzo, R.Rizzo (2011)
  O-Acetyl location on Cepacian, the principal exopolysaccharide of Burkholderia cepacia complex bacteria
  in Carbohydrate research (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• P.Cescutti, G.Impallomeni, D.Garozzo, R.Rizzo (literal)

Pagina inizio

• 2905 (literal)

Pagina fine

• 2912 (literal)

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• 346 (literal)

Rivista

• Carbohydrate research (Rivista)

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• ImpactFactor=1,898 (literal)

Note

• ISI Web of Science (WOS) (literal)

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• CNR ICTP (literal)

Titolo

• O-Acetyl location on Cepacian, the principal exopolysaccharide of Burkholderia cepacia complex bacteria (literal)

Abstract

• Cepacian is an exopolysaccharide produced by the majority of the isolates belonging to the Burkholderia cepacia complex bacteria, a group of 17 species, some of which infect cystic fibrosis patients, sometime with fatal outcome. The repeating unit of cepacian consists of a backbone having a trisaccharidic repeating unit with three side chains, as reported in the formula below. The exopolysaccharide is also acetylated, carrying from one to three acetyl esters per repeating unit, depending on the strain examined. The consequences of O-acetyl substitution in a polysaccharide are important both for its biological functions and for industrial applications, including the preparation of conjugated vaccines, since O-acetyl groups are important immunogenic determinants. The location of acetyl groups was achieved by NMR spectroscopy and ESI mass spectrometry and revealed that these substituents are scattered in non-stoichiometric ratio on many sugar residues in different positions, a feature which adds to the already unique carbohydrate structure of the polysaccharide. (literal)

Prodotto di

• Glicomica e Proteomica per la ricerca di biomarcatori per la diagnosi e la terapia di patologie congenite, tumorali e infiammatorie. (PM.P06.013.001) (Modulo)
• Istituto di chimica e tecnologia dei polimeri (ICTP) (Istituto)

Autore CNR

• GIUSEPPE IMPALLOMENI (Persona)
• DOMENICO GAROZZO (Unità di personale interno)

Incoming links:

Autore CNR di

• DOMENICO GAROZZO (Unità di personale interno)
• GIUSEPPE IMPALLOMENI (Persona)

Prodotto

• Istituto di chimica e tecnologia dei polimeri (ICTP) (Istituto)
• Glicomica e Proteomica per la ricerca di biomarcatori per la diagnosi e la terapia di patologie congenite, tumorali e infiammatorie. (PM.P06.013.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Carbohydrate research (Rivista)