The Complete Structure and Pro-inflammatory Activity of the Lipooligosaccharide of the Highly Epidemic and Virulent Gram-Negative Bacterium Burkholderia cenocepacia ET-12 (Strain J2315) (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• The Complete Structure and Pro-inflammatory Activity of the Lipooligosaccharide of the Highly Epidemic and Virulent Gram-Negative Bacterium Burkholderia cenocepacia ET-12 (Strain J2315) (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1002/chem.200601406 (literal)

Alternative label

• A. Silipo, A. Molinaro, T. Ieranò, A. De Soyza, L. Sturiale, D. Garozzo, C. Aldridge, P. A. Corris, C. M. Anjam Khan, R. Lanzetta, M. Parrilli (2007)
  The Complete Structure and Pro-inflammatory Activity of the Lipooligosaccharide of the Highly Epidemic and Virulent Gram-Negative Bacterium Burkholderia cenocepacia ET-12 (Strain J2315)
  in Chemistry - A European Journal; WILEY-V C H VERLAG GMBH, WEINHEIM (Germania)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• A. Silipo, A. Molinaro, T. Ieranò, A. De Soyza, L. Sturiale, D. Garozzo, C. Aldridge, P. A. Corris, C. M. Anjam Khan, R. Lanzetta, M. Parrilli (literal)

Pagina inizio

• 3501 (literal)

Pagina fine

• 3511 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 13 (literal)

Rivista

• Chemistry - A European Journal (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• No. Citazione=4; Autocitazione=0; Motore utilizzato per le citazioni=Isiwebofknowledge.com (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 11 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR, UNIVERSITA' di Napoli, The Freeman Hospital, University of Newcastle (literal)

Titolo

• The Complete Structure and Pro-inflammatory Activity of the Lipooligosaccharide of the Highly Epidemic and Virulent Gram-Negative Bacterium Burkholderia cenocepacia ET-12 (Strain J2315) (literal)

Abstract

• Members of genus Burkholderia include opportunistic Gram-negative bacteria that are responsible for serious infections in immunocompromised and cystic fibrosis (CF) patients. The Burkholderia cepacia complex is a group of microorganisms composed of at least nine closely related genomovars. Among these, B. cenocepacia is widely recognized to cause epidemics associated with excessive mortality. Species that belong to this strain are problematic CF pathogens because of their high resistance to antibiotics, which makes respiratory infections difficult to treat and impossible to eradicate. Infection by these bacteria is associated with higher mortality in CF and poor outcomes following lung transplantation. One virulence factor contributing to this is the pro-inflammatory lipopolysaccharide (LPS) molecules. Thus, the knowledge of the lipopolysaccharide structure is an essential prerequisite to the understanding of the molecular mechanisms involved in the inflammatory process. Such data are instrumental in aiding the design of antimicrobial compounds and for developing therapeutic strategies against the inflammatory cascade. In particular, defining the structure of the LPS from B. cenoce (literal)

Editore

• WILEY-V C H VERLAG GMBH (Editore)

Prodotto di

• Istituto di chimica e tecnologia dei polimeri (ICTP) (Istituto)
• Glicomica e Proteomica per la ricerca di biomarcatori per la diagnosi e la terapia di patologie congenite, tumorali e infiammatorie. (PM.P06.013.001) (Modulo)

Autore CNR

• DOMENICO GAROZZO (Unità di personale interno)
• LUISELLA STURIALE (Persona)

Insieme di parole chiave

• Parole chiave di "The Complete Structure and Pro-inflammatory Activity of the Lipooligosaccharide of the Highly Epidemic and Virulent Gram-Negative Bacterium Burkholderia cenocepacia ET-12 (Strain J2315)" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• DOMENICO GAROZZO (Unità di personale interno)
• LUISELLA STURIALE (Persona)

Prodotto

• Istituto di chimica e tecnologia dei polimeri (ICTP) (Istituto)
• Glicomica e Proteomica per la ricerca di biomarcatori per la diagnosi e la terapia di patologie congenite, tumorali e infiammatorie. (PM.P06.013.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Chemistry - A European Journal (Rivista)

Editore di

• WILEY-V C H VERLAG GMBH (Editore)

Insieme di parole chiave di

• Parole chiave di "The Complete Structure and Pro-inflammatory Activity of the Lipooligosaccharide of the Highly Epidemic and Virulent Gram-Negative Bacterium Burkholderia cenocepacia ET-12 (Strain J2315)" (Insieme di parole chiave)