Different substrates of non-sustained ventricular tachycardia in post-infarction patients with and without left ventricular dilatation (Articolo in rivista)

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  • Different substrates of non-sustained ventricular tachycardia in post-infarction patients with and without left ventricular dilatation (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.cardfail.2009.09.001 (literal)
Alternative label
  • Gianluca Di Bella; Claudio Passino; Giovanni Donato Aquaro; Daniele Rovai; Elisabetta Strata; Francesco Arrigo; Michele Emdin; Massimo Lombardi; Alessandro Pingitore. (2010)
    Different substrates of non-sustained ventricular tachycardia in post-infarction patients with and without left ventricular dilatation
    in Journal of cardiac failure (Print); Elsevier, Amsterdam (Paesi Bassi)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Gianluca Di Bella; Claudio Passino; Giovanni Donato Aquaro; Daniele Rovai; Elisabetta Strata; Francesco Arrigo; Michele Emdin; Massimo Lombardi; Alessandro Pingitore. (literal)
Pagina inizio
  • 61 (literal)
Pagina fine
  • 68 (literal)
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  • http://www.sciencedirect.com/science/article/pii/S1071916409010446 (literal)
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  • 16 (literal)
Rivista
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  • 8 (literal)
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  • 1 (literal)
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  • ISI Web of Science (WOS) (literal)
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  • Istituto di Fisiologia Clinica, CNR (literal)
Titolo
  • Different substrates of non-sustained ventricular tachycardia in post-infarction patients with and without left ventricular dilatation (literal)
Abstract
  • BACKGROUND: We investigated the relationship between nonsustained ventricular tachycardia (NSVT) and left ventricular (LV) dilatation, function, remodeling, and scar tissue extent in patients with previous myocardial infarction (MI). METHODS AND RESULTS: Eighty-two patients (ages 64+/-10 years) with first previous MI were referred for 24-hour electrocardiogram recording and cine and delayed enhancement (DE) cardiac magnetic resonance (CMR). LV volumes, ejection fraction, systolic wall thickening, sphericity index, and core and peri-infarctual areas of scar tissue by CMR were evaluated. LV dilatation was observed in 39 patients. Episodes of NSVT were recorded in 32 patients: 23 with LV dilatation and 9 without. In the entire population, NSVT was related to ejection fraction, LV volumes, LV mass, and sphericity index; end-systolic volume (P=.001) resulted in the only independent predictor at multivariate analysis. In patients without LV dilatation, the occurrence of NSVT was only positively related with percentage of contracting segments with DE (P=.008). Conversely, in patients with LV dilatation, increase in LV mass (P=.020) and end-systolic volume (P=.038) were independent predictors of NSVT. CONCLUSIONS: Necrotic and viable myocardium coexistence within the same wall segments predicted occurrence of NSVT in patients without LV dilatation, whereas LV mass and end-systolic volume were predictors of NSVT in those with LV dilatation. (literal)
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