Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.biortech.2011.07.036 (literal)

Alternative label

• Uhnakova, Bronislava; Ludwig, Roland; Peknicova, Jana; Homolka, Ladislav; Lisa, Ludmila; Sulc, Miroslav; Petrickova, Alena; Elzeinova, Fatima; Pelantova, Helena; Monti, Daniela; Kren, Vladimir; Haltrich, Dietmar; Martinkova, Ludmila (2011)
  Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products
  in Bioresource technology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Uhnakova, Bronislava; Ludwig, Roland; Peknicova, Jana; Homolka, Ladislav; Lisa, Ludmila; Sulc, Miroslav; Petrickova, Alena; Elzeinova, Fatima; Pelantova, Helena; Monti, Daniela; Kren, Vladimir; Haltrich, Dietmar; Martinkova, Ludmila (literal)

Pagina inizio

• 9409 (literal)

Pagina fine

• 9415 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 102 (literal)

Rivista

• Bioresource technology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 7 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 20 (literal)

Note

• ISI Web of Science (WoS) (literal)
• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Czech Academy of Sciences; University of Bodenkultur Wien; Czech Academy of Sciences; Czech Academy of Sciences; Czech Academy of Sciences; Consiglio Nazionale delle Ricerche (CNR) (literal)

Titolo

• Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products (literal)

Abstract

• Tetrabromobisphenol A (TBBPA) degradation was investigated using white rot fungi and their oxidative enzymes. Strains of the Trametes, Pleurotus, Bjerkandera and Dichomitus genera eliminated almost 1 mM TBBPA within 4 days. Laccase, whose role in TBBPA degradation was demonstrated in fungal cultures, was applied to TBBPA degradation alone and in combination with cellobiose dehydrogenase from Sclerotium rolfsii. Purified laccase from Trametes versicolor degraded approximately 2 mM TBBPA within 5 h, while the addition of cellobiose dehydrogenase increased the degradation rate to almost 2.5 mM within 3 h. Laccase was used to prepare TBBPA metabolites 2,6-dibromo-4-(2-hydroxypropane-2-yl) phenol (1), 2,6-dibromo-4-(2-methoxypropane-2-yl) phenol (2) and 1-(3,5-dibromo-4-hydroxyphen-1-y1)-2,2',6,6'-tetrabromo-4,4'-isopropylidene diphenol (3). As compounds 1 and 3 were identical to the TBBPA metabolites prepared by using rat and human liver fractions (Zalko et al., 2006), laccase can provide a simple means of preparing these metabolites for toxicity studies. Products 1 and 3 exhibited estrogenic effects, unlike TBBPA, but lower cell toxicity. (C) 2011 Elsevier Ltd. All rights reserved. (literal)

Prodotto di

• Applicazioni sintetiche della biocatalisi (PM.P03.009.002) (Modulo)
• Istituto di chimica del riconoscimento molecolare (ICRM) (Istituto)

Autore CNR

• DANIELA MONTI (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di chimica del riconoscimento molecolare (ICRM) (Istituto)
• Applicazioni sintetiche della biocatalisi (PM.P03.009.002) (Modulo)

Autore CNR di

• DANIELA MONTI (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Bioresource technology (Rivista)

Insieme di parole chiave di

• Keywords of "Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products" (Insieme di parole chiave)